Senior Scientist-R&D Oligo Synthesis

GRIFOLS, S.A.•San Diego, CA

7d•$120,000 - $172,500•Onsite

About The Position

Grifols Diagnostic Solutions in San Diego is seeking a highly skilled and motivated Scientist who is passionate about utilizing their expertise in oligonucleotide chemistry to provide oligonucleotide synthesis, purification, and analysis for R&D projects. The candidate will be responsible for a significant portion of a complex project or an entire less complex project or multiple less complex projects. The ideal candidate should understand the scope of the overall project in the scope of corporate strategy. They may manage 1 or more personnel and may represent R&D on a Core Team for a product development project.

Requirements

B.A. / B.S. Molecular Biology, Chemistry, Biochemistry or related field
M.S. Molecular Biology, Chemistry, Biochemistry or related field
Ph.D. Molecular Biology, Chemistry, Biochemistry or related field
7-9 years post-baccalaureate laboratory experience. Industrial experience preferred.
6-8 years laboratory experience post-M.S. without thesis. Industrial experience preferred.
5-7 years laboratory experience post M.S. with thesis. Industrial experience preferred.
Ph.D. with no post-doctoral research experience or 4-6 years industrial experience.
Ph.D. with post-doctoral research experience and 3-5 years industrial experience.

Nice To Haves

Industrial experience preferred.

Responsibilities

Perform automated oligonucleotide synthesis, deprotection and purification via standard phosphonamidite chemistry and chromatographic purification techniques.
Conduct oligonucleotide analysis using LCMS, MALDI, UV/VIS, and HPLC/UPLC techniques. Evaluate and identify impurities, degradation products, and synthesis by-products. Establish analytical protocols and support implementation of these protocols.
Lead and execute complex experiments, including providing guidance and direction on experimental design, analysis and interpretation of data, communication of results, and design of follow-up experiments. Responsible for subproject or project goals and deliverables.
Interact with peers and supervisors, both within the team as well as with other teams, to provide experimental summaries, design input, and ancillary team functions.
Maintain clearly written experimental records in both written and electronic formats.
Familiar with standard software tools utilized in instrument control, data analysis, and reporting results.