Senior Scientist, Immunology

MSD•Cambridge, MA

1d•Onsite

About The Position

Merck is seeking a Senior Scientist to join its Autoinflammation, Autoimmunity and Atopy disease team within the Immunology Discovery therapeutic area in Cambridge, Massachusetts. The role supports the development of novel therapeutics for allergic, autoimmune and inflammatory disease indications and contributes to the company’s strategic priorities in immunology. The Senior Scientist leads from the bench, independently designing and executing complex in vitro experiments. The position calls for expertise in immunological assays and technologies, sound data interpretation, organization, adaptability, and collaborative work across functional areas in a matrixed organization. The role is a regular employee position with a first-shift schedule. Domestic relocation is listed; visa sponsorship and travel are not available or required, respectively.

Requirements

Bachelor’s degree in biological sciences and 7 or more years of relevant pharmaceutical or biotechnology industry experience in immunology; or a master’s degree and 5 or more years of such experience; or a Ph.D. in biological sciences with relevant immunology experience in the pharmaceutical or biotechnology industry.
Expertise with multiparameter flow cytometry and a deep knowledge of technologies commonly used to assess immune endpoints.
Experience with primary immune cell isolation and stimulation, proliferation and apoptosis assays, immunoassay techniques and platforms such as Western blot, ELISA and Mesoscale, and RT-PCR.
Competence with standard scientific data-analysis software, including Microsoft Excel and GraphPad Prism, and Microsoft Word and PowerPoint.
Good data handling and recording skills, with the ability to interpret moderately complex data sets and draw appropriate conclusions.
Excellent organization and ability to multitask and manage multiple projects.
Ability to adapt to rapidly changing project priorities and define and meet aggressive timelines.
Commitment to collaborative work across functional areas in a matrixed organization.
Curiosity, self-motivation, and excellent verbal and written communication skills.

Nice To Haves

Expertise in allergic inflammation and autoimmunity to execute complex immunological experiments.
Experience with preclinical model systems and human blood and disease tissues.
Background in clinical immunology and translational biomarkers.

Responsibilities

Independently design and execute complex in vitro experiments to support early development of novel therapeutics for allergic, autoimmune and inflammatory disease indications.
Lead from the bench and demonstrate strong scientific acuity.
Develop in vitro and in vivo assays to investigate immune function.
Handle and record data, interpret moderately complex data sets, and draw appropriate conclusions.
Manage multiple projects and meet aggressive timelines while adapting to changes in priorities.
Collaborate across functional areas within a matrixed organization.