Senior Scientist, Biology-Discovery
About The Position
We’re seeking an experienced Senior Scientist to join the Infectious Disease and Vaccines department at our research site in West Point, PA. The candidate will have a primary role in a team responsible for the discovery and development of novel antiviral treatments. The candidate will independently design and execute experiments to interrogate fundamental virus biology, virus-host interactions, and immunological responses using various biochemical and cell-based assays. The candidate should have a strong background in virology, immunoassay and genomic technologies, cell biology, animal pharmacology, and general knowledge of infectious disease drug development. We value creative thinking, teamwork, and independent analytical problem solving. If you are a highly motivated team player with a strong desire to impact basic research and translational medicine, we invite you to consider joining our team.
Requirements
- BS/BA degree in Biology or Biomedical Sciences with a minimum 7 years of experience in industry and/or academia, OR MS degree in Biology or Biomedical Sciences with 4 years of experience in industry and or academia, OR PhD with >1 year postdoctoral experience.
- Mammalian cell culture — maintenance and manipulation of immortalized cell lines and primary cells.
- Cell-based antiviral assays — design, execution, and analysis of infection and drug-response assays.
- RT-qPCR/qPCR and nucleic acid extraction — robust RNA/DNA isolation and quantitative PCR for viral load and gene expression.
- Protein analysis — Western blotting and basic protein quantitation.
- Virology fundamentals — safe handling, propagation, and titration of viruses (plaque/titer or focus-forming assays).
- Keen awareness of emerging biology and new technologies.
- Good laboratory practices and documentation — accurate record-keeping, adherence to biosafety procedures, and reproducible experimental workflows.
- Adaptability
- Assay Development
- Biochemical Assays
- Biomedical Sciences
- Cell-Based Assays
- Cell Cultures
- Cell Culture Techniques
- Cell Line Development
- Detail-Oriented
- Drug Target Identification
- Flow Cytometry
- High Content Screening
- Image Acquisition
- Immunoassays
- Immunology
- Infectious Disease
- Influenza
- Mammalian Cell
- Mammalian Cell Culture
- Molecular Biology
- Personal Initiative
- Protein Analysis
- Protein Purifications
- Team Player
Nice To Haves
- High-content or fluorescence microscopy — image acquisition and basic image analysis for phenotypic readouts.
- Data analysis and statistics — ability to analyze dose–response, kinetics, and experimental data using tools such as R, or Python.
Responsibilities
- Independently design and execute experiments to interrogate fundamental virus biology, virus-host interactions, and immunological responses using various biochemical and cell-based assays.
- Contribute to the discovery and development of novel antiviral treatments.
- Maintain and manipulate immortalized cell lines and primary cells.
- Design, execute, and analyze cell-based antiviral assays, including infection and drug-response assays.
- Perform RT-qPCR/qPCR and nucleic acid extraction for viral load and gene expression analysis.
- Conduct protein analysis, including Western blotting and basic protein quantitation.
- Safely handle, propagate, and titrate viruses using plaque/titer or focus-forming assays.
- Maintain accurate records, adhere to biosafety procedures, and ensure reproducible experimental workflows.
- Stay keenly aware of emerging biology and new technologies.
Benefits
- medical, dental, vision healthcare and other insurance benefits (for employee and family)
- retirement benefits, including 401(k)
- paid holidays
- vacation
- compassionate and sick days
- annual bonus and long-term incentive, if applicable
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What This Job Offers
Job Type
Full-time
Career Level
Senior
