Scientist - RC Discovery Biology
About The Position
Fusion Pharmaceuticals, a member of the AstraZeneca Group, is advancing next generation radio conjugates as precision medicines for cancer. By combining Fusion’s deep radiopharmaceutical expertise with AstraZeneca’s global scale and reach, we are working to translate bold science into meaningful outcomes for patients. This is an opportunity to join a collaborative, innovation-driven team at the forefront of oncology research. We are seeking a highly motivated, hands-on Scientist, Bioscience, to support later-stage radio conjugate programs through assay development, pre-clinical profiling of mechanisms-of-action, and in vitro drug-drug combination studies. This role is ideal for a strong laboratory scientist who thrives in a fast-paced research environment and enjoys working across disciplines to generate high-quality data that advances discovery and development programs. The successful candidate will contribute to the design, execution, analysis, and reporting of a broad range of cellular, molecular, and histological assays. Working closely with cross-functional colleagues in biology, in vivo pharmacology and radiochemistry, this individual will provide cross-program support to advance targeted radio therapy development.
Requirements
- MSc. with at least 2 years or B.Sc. with at least 5 years of post-graduate academic or industry experience in Molecular/Cell Biology, Immunology, Biochemistry, or related disciplines.
- Demonstrated experience with biochemical and cell biology methods such as cell culture, CRISPR/Cas9, immunohistochemistry, flow cytometry, and Western blotting.
- Experience developing, optimizing, and executing cell-based assays.
- Excellent organizational skills and demonstrated record keeping abilities
- Demonstrated safe handling of chemical and biohazardous materials.
- Ability to adapt to, perform, and develop unfamiliar methods in a rapidly evolving research environment.
Nice To Haves
- Experience in handling radioisotopes is considered an asset.
Responsibilities
- Independently executes routine in vitro drug mechanism-of-action and cell viability experiments by applying techniques of cell and molecular biology (e.g. cell culture, flow cytometry, immunoblotting, immunofluorescence).
- Contributes to cell line model development (lentiviral transduction, CRISPR/Cas9), and mammalian tissue processing or analysis (e.g. immunohistochemistry, immunoblotting, RNA/DNA sequencing sample preparation).
- Communicates the results to team members and is involved in the interpretation of data.
- Supports a team and works collaboratively with project managers to ensure the efficient relay of information and forward translation of data.
- Maintains a well-developed understanding of approaches to radio conjugate mechanism-of-action and development and applies a broader functional knowledge of the procedures used by diverse project groups to support the department where needed.
- Assesses and reports data in a clear and concise manner, with a clear understanding of its implications within the overall context of drug discovery.
- Provides technical instruction to the team and allocates administrative work where possible.
- Shares relevant external published papers with peers.
- Communicates and shares information between distinct projects within the bioscience function and across other functions.
- Ensures own work, and work of peers, is compliant with Good Laboratory Practice, Safety, Health and Environment standards and all other relevant internal AstraZeneca standards and external regulations.
Benefits
- Annual base salary for this position ranges from 82,377.60 to 108,120.60.
- Annual Variable Pay Bonus/Short Term Incentive opportunity
- Eligibility to participate in our equity-based long-term incentive program (if applicable to role).
- Competitive Flex Benefits & Retirement Savings Program
- 4 weeks’ paid vacation
- Annual Personal Days.
- Contract Benefits Program (for Fixed Term Contract/Temporary positions excluding students)
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What This Job Offers
Job Type
Full-time
Career Level
Senior
