Senior Manager Manufacturing – Night Shift Operations Performance & Integration

Amgen•New Albany, OH

About The Position

The Night Shift Senior Manager of Manufacturing is responsible for establishing and sustaining a strong night-shift operating system. The role provides off-shift operational direction for Commercial Operations and Project-based Commissioning and Qualification (C&Q) coverage, ensuring appropriate cross-functional resources are engaged, issues are escalated and resolved urgently, and manufacturing performance is actively managed across the shift. The position partners with Engineering, Automation, Quality Assurance, Technology, Maintenance, Supply Chain/Warehouse, and Capital Projects. The role serves as a senior Manufacturing integration point during significant night-shift operational events; establishes the shift’s Tier structure, operating cadence, escalation model, and performance-management routines; and coordinates resources to maintain safe, compliant, and reliable operations. It monitors performance across production lines and partners with daytime leaders to identify and execute continuous-improvement opportunities. The Senior Manager also provides coaching and situational leadership to Front Line Managers during complex operational events.

Requirements

Meet one of the following education and experience combinations in GMP manufacturing, process development, combination device, and/or manufacturing-focused Six Sigma Lean operational excellence: doctorate degree and 2 years of experience; master’s degree and 6 years; bachelor’s degree and 8 years; associate’s degree and 10 years; or high school diploma/GED and 12 years.
At least 2 years of experience directly managing people and/or leadership experience leading teams, projects, programs, or directing resource allocation. This experience may run concurrently with the required technical experience.

Responsibilities

Serve as the senior Manufacturing integration point across night-shift operations during significant operational events.
Establish and sustain the night-shift Tier structure, operating cadence, escalation model, and performance-management routines.
Coordinate Manufacturing, Quality Assurance, Engineering, Automation, Maintenance, Supply Chain/Warehouse, and other site resources to maintain safe, compliant, and reliable operations.
Escalate significant resource constraints, technical barriers, competing priorities, and unresolved operational issues to appropriate site or functional leadership.
Monitor night-shift Manufacturing performance across production lines, including downtime, OEE, schedule attainment, recurring interruptions, escalation effectiveness, and chronic losses.
Partner with the daytime Manufacturing Senior Manager, Continuous Improvement Senior Manager, and MFG Process Support Senior Manager to identify, prioritize, and execute off-shift improvement opportunities.
Support improvement efforts involving 5S, visual management, standard work, workplace organization, waste reduction, flow improvement, and training operating discipline.
Provide coaching and situational leadership to Front Line Managers during complex operational events.