Senior Manager, Business Operations

Takeda•Lexington, MA
•$137,000 - $215,270•Onsite

About The Position

The Senior Manager, Business Operations leads business operations for assigned Pharmaceutical Sciences (PharmSci) functions, partnering with function heads and their Senior Leadership Teams to translate strategic priorities into effective operational plans and measurable outcomes. The role independently leads complex, cross-functional initiatives; establishes governance, accountability, and performance monitoring; and anticipates operational risks and resource needs. Through actionable analysis, process and systems improvements, and support for leadership decision-making, the role strengthens the efficiency and effectiveness of PharmSci operations. The position reports to the Director, Pharmaceutical Sciences Clinical Manufacturing Business Operations and is based in Lexington, Massachusetts.

Requirements

  • Bachelor’s degree in a scientific discipline, Business Administration, Operations Management, or a related field.
  • 10 or more years of relevant industry experience, including demonstrated experience independently leading complex, cross-functional initiatives and accountability for governance, risk management, decision support, and measurable outcomes.
  • Ability to independently lead initiatives from planning through implementation, manage interdependencies, and deliver measurable outcomes.
  • Strong analytical and financial skills, including ability to interpret operational data, budgets, resource plans, and performance trends and turn them into actionable recommendations.
  • Ability to influence senior and cross-functional stakeholders, establish accountability, and drive outcomes without direct authority.
  • Excellent communication, facilitation, and presentation skills, including ability to prepare clear, concise, decision-ready materials for leadership.
  • Strong organizational skills, judgment, attention to detail, and ability to prioritize multiple complex activities.
  • Proficiency with Microsoft Outlook, Word, Excel, and PowerPoint.
  • Self-directed and proactive, with comfort making decisions within delegated authority and escalating material issues appropriately.

Nice To Haves

  • Advanced degree.
  • Experience in pharmaceutical, biotech, or other regulated environments.
  • Experience with Power BI and SharePoint.
  • Project management, Lean, or Six Sigma certification.

Responsibilities

  • Lead complex operational initiatives for assigned PharmSci functions, translating strategic priorities into plans with defined outcomes, milestones, owners, dependencies, and measures of progress.
  • Establish and lead governance and operating routines to review progress, resolve issues, track decisions, and ensure timely completion of cross-functional commitments.
  • Identify operational risks, resource constraints, and dependencies; develop mitigation options, drive in-scope actions, and escalate significant issues and tradeoffs to leadership.
  • Lead budgeting and resource-planning activities, including headcount tracking and MRP, MYC, and Capex processes; analyze actuals, projections, and variances and provide recommendations to leaders.
  • Develop and maintain operational reporting, dashboards, and tracking mechanisms that provide leaders insight into performance, priorities, risks, and resource needs.
  • Lead process-improvement initiatives in areas such as onboarding, communications, planning, and systems interactions; implement changes and assess their effectiveness.
  • Own and improve function-level operating processes and infrastructure, including resource repositories, onboarding practices, functional communications, and training materials.
  • Lead preparation and coordination of leadership meetings, Town Halls, and other forums, ensuring agendas, pre-reads, decisions, and follow-up actions support effective leadership and timely information flow.
  • Partner with function heads and cross-functional stakeholders on requests, nominations, and organizational initiatives, driving alignment and follow-through.
  • Lead vendor and contracting activities within scope, partnering with Contracts, Legal, Compliance, and relevant stakeholders to address issues and escalate exceptions.
  • Identify opportunities to improve operational tools and information flow; develop practical solutions using tools such as Power BI and SharePoint, and guide adoption.
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