Senior Manager, Business Operations

Takeda•Lexington, MA

3d•Onsite

About The Position

The Senior Manager, Business Operations leads business operations for assigned Pharmaceutical Sciences (PharmSci) functions, partnering with function heads and their Senior Leadership Teams to translate strategic priorities into operational plans and measurable outcomes. The role independently leads complex cross-functional initiatives; establishes governance, accountability, and performance monitoring; anticipates operational risks and resource needs; and provides analysis and process improvements that support effective leadership decisions and strengthen PharmSci operations. The position reports to the Director, Pharmaceutical Sciences Clinical Manufacturing Business Operations and is based in Lexington, Massachusetts.

Requirements

Bachelor’s degree in a scientific discipline, Business Administration, Operations Management, or a related field.
At least 10 years of relevant industry experience, including demonstrated experience independently leading complex cross-functional initiatives and accountability for governance, risk management, decision support, and measurable outcomes.
Ability to independently lead initiatives from planning through implementation, manage interdependencies, and deliver measurable outcomes.
Strong analytical and financial skills, including interpreting operational data, budgets, resource plans, and performance trends and turning them into actionable recommendations.
Ability to influence senior and cross-functional stakeholders, establish accountability, and drive outcomes without direct authority.
Excellent communication, facilitation, and presentation skills, including preparing clear, concise, decision-ready materials for leadership.
Strong organizational skills, judgment, attention to detail, and ability to prioritize multiple complex activities.
Proficiency with Microsoft Outlook, Word, Excel, and PowerPoint.
Self-directed and proactive, with the ability to make decisions within delegated authority and appropriately escalate material issues.

Nice To Haves

Advanced degree.
Experience in pharmaceutical, biotech, or other regulated environments.
Experience with Power BI and SharePoint.
Project management, Lean, or Six Sigma certification.

Responsibilities

Lead complex operational initiatives for assigned PharmSci functions, translating strategic priorities into plans with defined outcomes, milestones, owners, dependencies, and progress measures.
Establish and lead governance and operating routines to review progress, resolve issues, track decisions, and ensure timely completion of cross-functional commitments.
Identify operational risks, resource constraints, and dependencies; develop mitigation options, drive actions within scope, and escalate significant issues and tradeoffs to leadership.
Lead budgeting and resource planning, including headcount tracking and MRP, MYC, and Capex processes; analyze actuals, projections, and variances and recommend actions to leaders.
Develop and maintain operational reporting, dashboards, and tracking mechanisms to provide leaders with insight into performance, priorities, risks, and resource needs.
Lead process-improvement initiatives in areas such as onboarding, communications, planning, and systems interactions; implement changes and assess their effectiveness.
Own and improve function-level operating processes and infrastructure within scope, including resource repositories, onboarding practices, functional communications, and training materials.
Lead preparation and coordination of leadership meetings, Town Halls, and other forums, including agendas, pre-reads, decisions, and follow-up actions.
Partner with function heads and cross-functional stakeholders on requests, nominations, and organizational initiatives, driving alignment and follow-through.
Lead vendor and contracting activities within scope, partnering with Contracts, Legal, Compliance, and relevant stakeholders to address issues and escalate exceptions.
Identify opportunities to improve operational tools and information flow; develop practical solutions using tools such as Power BI and SharePoint, and support their adoption.