Senior Manager, Accounting

Definium Therapeutics • San Diego, CA

2d • Hybrid

About The Position

Definium Therapeutics, formerly known as Mind Medicine, is a clinical stage biopharmaceutical company developing novel product candidates to treat brain health disorders. Our mission is to be the global leader in the development and delivery of treatments that unlock new opportunities to improve patient outcomes. We are developing a pipeline of innovative product candidates, with and without acute perceptual effects, targeting neurotransmitter pathways that play key roles in brain health. Founded in 19, we are continuously expanding our presence and global footprint. We are constantly searching for high-impact individuals in various clinical, technical and business operations domains to strengthen our team of patient-centric, intelligent individuals. Reporting to the Corporate Controller, the Sr. Manager, Accounting will play a key role in our accounting team, with a strong emphasis on SOX 404(b) compliance and equity (stock-based compensation) accounting. This role will be responsible for designing, implementing, and maintaining internal controls, as well as overseeing the accounting and reporting for equity transactions in a fast-paced, public company environment.

Requirements

• Bachelor’s degree required, degree in Accounting, Finance, or related field preferred, CPA License preferred
• Minimum 7 years of progressive accounting experience required, life science industry preferred
• Previous experience with Shareworks and NetSuite preferred
• Previous experience with equity administration and technical accounting required
• Previous experience with accounting in a publicly traded company required
• Experience supporting accounting or SOX considerations related to commercial operations, business process changes, or company scale-up initiatives preferred
• Deep, hands-on knowledge of SOX 404(b) requirements and internal control frameworks (e.g., COSO)
• Excellent written and verbal communication skills, along with the ability to present numeric data effectively
• Proven experience working with external auditors in a SOX-compliant environment
• Demonstrated ability to handle highly confidential information with sound judgment and discretion
• Intermediate-to-advanced MS Office skills (Outlook, Word, Excel, PowerPoint)

Nice To Haves

• degree in Accounting, Finance, or related field preferred
• CPA License preferred
• life science industry preferred
• Previous experience with Shareworks and NetSuite preferred
• Experience supporting accounting or SOX considerations related to commercial operations, business process changes, or company scale-up initiatives preferred

Responsibilities

• Oversee accounting for stock-based compensation, including stock options, RSUs, PSUs, and ESPP
• Ensure accurate and timely recognition of equity compensation expense in accordance with ASC 718
• Manage equity-related reports and data from Shareworks
• Review and validate fair value assumptions (e.g., Black-Scholes inputs, peer companies)
• Coordinate with Legal, HR, and external valuation specialists on equity grants and modifications
• Support preparation of equity disclosures for SEC filings (10-K, 10-Q, proxy)
• Help lead the design, implementation, and ongoing maintenance of internal controls in compliance with SOX 404(b)
• Partner with internal and external auditors to support control walkthroughs, testing, and remediation efforts
• Evaluate control deficiencies and drive timely remediation plans
• Maintain and update process flowcharts, risk control matrices (RCMs), and control documentation
• Ensure readiness for external auditor attestation under SOX 404(b)
• Collaborate cross-functionally to strengthen control environment and ensure adherence to company policies
• Support month-end and quarter-end close processes related to equity and other assigned areas
• Support commercial-related initiatives that intersect with equity compensation and SOX controls, including evaluation of control impacts from new or evolving processes
• Perform other accounting, compliance, and internal control-related responsibilities as needed to support the company’s financial reporting and growth objectives

Benefits

• 100% paid health benefits including Medical, Dental and Vision for you and your dependents
• 401(k) program with company match and vesting after the turn of the first month after your start date
• Flexible time off
• Generous parental leave and some fun fringe perks!

What This Job Offers

• Job Type: Full-time
• Career Level: Manager
• Number of Employees: 1,001-5,000 employees