Senior LIMS Engineer, Prenatal

BillionToOne•Union City, CA
•$152,309 - $163,189•Onsite

About The Position

BillionToOne is seeking a Senior LIMS Engineer to join its Laboratory Information Management System (LIMS) team supporting clinical patient testing in a high-throughput CLIA laboratory. The role focuses on deepening integration between existing BillionToOne software and the clinical LIMS, owning critical portions of the LIMS sample-processing pipeline, and maintaining, improving, and building LIMS applications, tools, and infrastructure. The position develops and supports software and systems used in clinical laboratory operations, working with cross-functional teams to gather requirements, conduct user acceptance testing, incorporate feedback, complete quality-system paperwork, and launch products. The engineer also troubleshoots issues affecting sample handling, automation, and infrastructure; contributes to code reviews, verifications, and validations; supports compliance with corporate and regulatory requirements; and mentors junior engineers and technical colleagues. This is an onsite role at the Union City lab, with flexibility to work from home or at the Menlo Park site when applicable.

Requirements

  • Bachelor's degree with a biological or computational focus.
  • Experience with both Python and AI-assisted development.
  • At least 5 years of experience developing LIMS, applications, or customer-facing tools.
  • Ability to troubleshoot and diagnose advanced technical issues.
  • Experience developing scripting solutions to automation problems.
  • Strong attention to detail and ability to work flexibly under accelerated timeframes.
  • Highly organized, with strong written and verbal communication skills.
  • Creative problem-solving ability and enjoyment of varied daily tasks.

Nice To Haves

  • Experience working in a CLIA laboratory, medical device, or pharmaceutical environment.
  • Experience with data analysis using Python, SQL, or Excel.
  • Familiarity with Quality Management Systems and related regulations, such as 21 CFR Part 11 and ISO 13485.

Responsibilities

  • Develop modern, user-friendly, secure software for the clinical laboratory.
  • Solve complex issues involving sample handling, automation, or infrastructure that affect laboratory processing.
  • Work with cross-functional teams to gather requirements, facilitate user acceptance testing, incorporate feedback, complete quality-system paperwork, and launch products.
  • Work independently and prioritize projects based on company goals.
  • Mentor junior LIMS engineers and technical members of other teams in best practices.
  • Participate in LIMS code reviews, verifications, and validations.
  • Ensure compliance with relevant corporate and regulatory requirements.

Benefits

  • Multiple medical benefit options; employee premiums are paid for select plans, and dependents are covered up to 80%.
  • 16 weeks of paid Family Bonding Leave for new parents, paid at 100%.
  • Supplemental fertility benefits coverage.
  • Retirement savings program with a 4% company match.
  • Paid time off increases with tenure.
  • Latest hardware, including laptops, laboratory equipment, and facilities.
  • Daily on-site lunches provided from local eateries.
  • On-campus state-of-the-art gym and restaurant.
  • Free on-site EV charging.
  • Equity options offering.
  • Corporate bonus program.
  • On-site work environment with flexibility to work from home or the Menlo Park site when applicable.
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