Senior LIMS Engineer, Prenatal

BillionToOne•Union City, CA
•$152,309 - $163,189•Onsite

About The Position

BillionToOne is seeking a Senior LIMS Engineer to join its Laboratory Information Management System (LIMS) team and support clinical patient testing in a high-throughput CLIA lab. The role focuses on deepening integration between existing BillionToOne software and the clinical LIMS, owning critical parts of the LIMS sample-processing pipeline, and maintaining, improving, and building LIMS applications, tools, and infrastructure. The engineer will develop secure, user-friendly software for the clinical lab and address complex issues involving sample handling, automation, and infrastructure. The position works with cross-functional teams to gather requirements, conduct user acceptance testing, incorporate feedback, complete quality-system paperwork, and launch products. It also includes working independently, prioritizing work around company goals, mentoring junior engineers and technical colleagues, participating in code reviews and verification and validation, and ensuring compliance with corporate and regulatory requirements. This is an onsite role at BillionToOne's Union City lab, with flexibility to work from home or at the Menlo Park site when applicable.

Requirements

  • Bachelor's degree with a biological or computational focus.
  • Experience with both Python and AI-assisted development.
  • At least 5 years of experience developing LIMS, applications, or customer-facing tools.
  • Ability to troubleshoot and diagnose advanced technical issues.
  • Experience developing scripting solutions to automation problems.
  • Strong attention to detail and ability to work flexibly under accelerated timeframes.
  • Strong organization and written and verbal communication skills.
  • Creative problem-solving skills and enjoyment of varied daily tasks.

Nice To Haves

  • Experience working in a CLIA lab, medical device, or pharmaceutical environment.
  • Experience with data analysis using Python, SQL, or Excel.
  • Familiarity with Quality Management Systems and related regulations, such as CFR 21 Part 11 and ISO 13485.

Responsibilities

  • Develop modern, user-friendly, secure software for the clinical lab.
  • Solve complex issues in sample handling, automation, or infrastructure that affect lab processing.
  • Work with cross-functional teams to gather requirements, facilitate user acceptance testing, iterate on feedback, file quality-system paperwork, and launch products.
  • Work independently and prioritize projects based on company goals.
  • Mentor junior LIMS engineers and technical members of other teams in best practices.
  • Participate in LIMS code reviews, verifications, and validations.
  • Ensure compliance with relevant corporate and regulatory requirements.
  • Deepen integration between existing BillionToOne software and the clinical LIMS.
  • Take ownership of critical portions of the LIMS sample-processing pipeline.
  • Maintain, improve, and build LIMS applications, tools, and infrastructure.

Benefits

  • Multiple medical benefit options; employee premiums are paid 100% for select plans, and dependents are covered up to 80%.
  • 16 weeks of paid Family Bonding Leave at 100% pay for new parents.
  • Supplemental fertility benefits coverage.
  • Retirement savings program with a 4% company match.
  • Paid time off that increases with tenure.
  • Latest hardware, including a laptop, lab equipment, and facilities.
  • Daily on-site lunches from local eateries.
  • On-campus amenities including a gym and restaurant.
  • Free on-site EV charging.
  • Equity options.
  • Corporate bonus program.
  • Free healthcare options.
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