Senior LIMS Engineer, Prenatal

BillionToOne•Union City, CA
•Onsite

About The Position

BillionToOne is seeking a Senior LIMS Engineer to support clinical patient testing in its high-throughput CLIA laboratory. The role focuses on deepening integration between existing BillionToOne software and the clinical LIMS, taking ownership of critical portions of the LIMS sample-processing pipeline, and maintaining, improving, and building LIMS applications, tools, and infrastructure. The position is onsite at the Union City lab, with flexibility to work from home or at the Menlo Park site when applicable.

Requirements

  • Bachelor’s degree with a biological or computational focus.
  • Experience with Python and AI-assisted development.
  • At least 5 years of experience developing LIMS, applications, or customer-facing tools.
  • Ability to troubleshoot and diagnose advanced technical issues.
  • Experience developing scripting solutions to automation problems.
  • Strong attention to detail and ability to work flexibly under accelerated timeframes.
  • Strong organizational, written communication, and verbal communication skills.
  • Creative problem-solving ability and interest in varied daily tasks.

Nice To Haves

  • Experience working in a CLIA lab, medical device company, or pharmaceutical company.
  • Experience with data analysis using Python, SQL, or Excel.
  • Familiarity with Quality Management Systems and related regulations, such as CFR 21 Part 11 and ISO 13485.

Responsibilities

  • Develop modern, user-friendly, secure software for the clinical lab.
  • Resolve complex issues in sample handling, automation, or infrastructure that affect laboratory processing.
  • Work with cross-functional teams to gather requirements, facilitate user acceptance testing, incorporate feedback, complete quality-system paperwork, and launch products.
  • Work independently and prioritize projects according to company goals.
  • Mentor junior LIMS engineers and technical members of other teams in best practices.
  • Participate in LIMS code reviews, verifications, and validations.
  • Ensure compliance with applicable corporate and regulatory requirements.

Benefits

  • Multiple medical benefit options; employee premiums are paid for select plans, and dependent coverage is provided up to 80%.
  • 16 weeks of paid family bonding leave for new parents, paid at 100%.
  • Supplemental fertility benefits coverage.
  • Retirement savings program with a 4% company match.
  • Paid time off that increases with tenure.
  • Latest hardware, lab equipment, and facilities.
  • Daily on-site lunches from local eateries.
  • On-campus amenities including a gym and restaurant.
  • Free on-site EV charging.
  • Equity options and a corporate bonus program.
  • Some company healthcare options are free.
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