Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. With our transformation into a fully integrated oncology company well underway, it’s an exciting time to be part of Team Olema. Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in Q1 2027 which, if positive, could lead to our first potential approval and commercial launch in 2028. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant could transform the metastatic breast cancer treatment paradigm and provide access to a $15 billion global market opportunity. Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape – particularly in combination with palazestrant. We recently presented encouraging Phase 1 monotherapy data from this program across multiple solid tumor types, are advancing patient enrollment in the ongoing combination arms in MBC, and expect to initiate a Phase 1 study of OP-3136 in combination with Bayer’s darolutamide in metastatic castration-resistant prostate cancer by the end of this year. Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and passionate colleagues dedicated to helping the patients we serve feel better, longer. Team Olema possesses a deep commitment to a shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, the drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. We are a small group of nimble self-starters who bring consistency in our quest for the extraordinary every single day. If you’re ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together – for our patients, for your career, and for what’s beyond. About the Role >>> Senior IT Support Engineer As the Sr. IT Support Engineer reporting to the Senior Director of IT Infrastructure & Operations, you will provide high level of support, employee onboarding, offboarding and employee experience, while providing hands-on office support for IT & Facilities management for our Boston office. We are seeking an experienced, customer-focused individual to join our IT Operations team. This role is based out of our Boston office, is fully onsite, and requires in-office presence. Your work will primarily encompass: IT Operations & Support Deliver high level support to executives, senior leaders, and other employees, including proactive support for laptops, mobile devices, collaboration tools, conference rooms, and travel needs. Coordinate timely resolution of complex issues with internal IT teams, managed service providers, and technology vendors; remain accountable through final resolution. Onboarding, Offboarding and Employee Experience Lead the IT onboarding and offboarding process in partnership with people and culture, hiring managers, and IT teams, ensuring equipment, accounts, access, communications, and asset recovery are handled according to established procedures. Plan and deliver new-hire IT orientation sessions, introducing employees to their devices, core applications, collaboration tools, security expectations, support channels, and self-service resources. Maintain onboarding/offboarding checklists, standard communications, orientation materials, and process documentation; identify and implement improvements that increase consistency and reduce time to productivity. Onsite Delivery and Service Operations Install, configure, maintain, and troubleshoot end-user hardware, software, peripherals, mobile devices, Windows and macOS operating systems, business applications, and workplace technology. Serve as the Boston onsite delivery lead, coordinating daily support coverage, prioritizing work, managing escalations from the 24x7 helpdesk MSP, and ensuring a high-quality employee support experience. Log, prioritize, and resolve user incidents and requests received in-person, by phone, email, or ticketing systems; meet service-level agreements, prioritize by urgency and business impact, communicate status, and remain accountable through resolution. Troubleshoot issues across network configuration, system installation, device connectivity, and business applications; perform root-cause analysis, administer user accounts and permissions, and escalate complex issues while tracking resolution. Monitor system performance, apply approved updates and patches, and coordinate backups; maintain knowledge articles and train users on new systems, software, secure technology use, and IT best practices. Support conference rooms, AV, desk setups, and office technology; maintain accurate asset records, collaborate with IT teams and service providers, and proactively identify technology and security risks. Workplace Coordination Help manage general office facilities tasks, including maintaining the cleanliness and organization of shared spaces and restocking snack and supply areas. Report facility issues promptly and coordinate resolution with the property manager and external vendors as directed; assist with general maintenance to help ensure a safe, clean, and well-functioning workplace. Participate in workspace management and office expansion/moves. Other duties as assigned.
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Job Type
Full-time
Career Level
Senior
Education Level
Associate degree