Senior Financial Analyst, Clinical Finance
About The Position
Pathos is seeking a Senior Financial Analyst, Clinical Finance to own the financial side of its clinical vendor base, from forecasting and contract review through invoice review and monthly accruals. The role is intended for an analyst with 2 to 4 years of biotech or pharma finance experience who is ready to manage a process end to end. The position reports to the SVP of Finance and partners with Clinical Operations, accounting, Legal, CROs and vendors. A key focus is tracking changes in each trial and ensuring budgets, forecasts and accruals reflect the latest plans. The role also uses AI agents and automation to build repeatable processes that reduce errors, improve accuracy and surface insights. The analyst owns clinical trial forecasting by vendor, study and cost category; reviews vendor contracts, invoices and spending; supports clinical procurement; prepares monthly clinical accruals; and reports actual-versus-forecast results. The role also maintains reconciled spend dashboards and schedules, supports accounting close, and provides documented expense support for audits and investor diligence. This is a hybrid role based in Pathos’s New York City office, with in-person attendance on Tuesdays, Wednesdays and Thursdays.
Requirements
- Bachelor’s degree in finance, accounting, economics or a related field.
- 2 to 4 years as a financial analyst at a biotech, pharma company or CRO, with direct exposure to R&D or clinical trial costs across multiple studies.
- Working knowledge of clinical trial contracting and billing, including MSAs, SOWs, change orders, pass-through costs, site payments and prefunded deposits.
- Experience building forecasts and variance analyses.
- Understanding of accrual accounting and month-end close, including the ability to build an accrual from operational data with documented support.
- Advanced Excel skills, including building models others can follow, audit and update.
- Strong interest in using AI tools and automation in daily work, with examples of workflows streamlined or rebuilt to reduce manual effort and errors.
- Confidence to question vendor invoices and judgment to collaborate with Clinical Operations.
Nice To Haves
- Hands-on clinical accrual ownership for one or more studies.
- Experience with QuickBooks Online and Bill.com, or similar ERP and accounts payable tools.
- Exposure to oncology trials.
- Experience on a small finance team covering several roles.
- CPA progress or MBA coursework.
Responsibilities
- Build and own clinical trial forecasts by vendor, study and cost category, incorporating changes in enrollment, site activation, protocols, scope and timelines.
- Provide clinical inputs for the annual budget, quarterly reforecasts and cash runway models.
- Maintain a vendor tracker matching invoice lines to MSAs, SOWs, work orders and executed change orders, and track remaining contract value by category.
- Support the clinical accounts payable process by tracking invoices, tying them to purchase orders and studies, identifying duplicates, and routing them to Clinical Operations for review.
- Review vendor billing for hours, units, milestones and pass-through costs against contract terms and study progress; flag out-of-scope, overstaffed or premature resource use before invoice approval.
- Track CRO prefunded deposits and site grant funds, including amounts prepaid, applied and credited back.
- Maintain an exceptions log and escalate items for resolution with vendors or Pathos decision-makers.
- Compare invoiced and accrued spend with forecasts each month and explain variances.
- Maintain the clinical spend dashboard and reconcile it to Pathos billing and accounting platforms.
- Prepare monthly spend, burn and variance reporting for the SVP of Finance and Clinical Operations leadership.
- Support the finance side of contracting by reviewing SOW and change-order budgets, comparing pricing and rate cards with prior work, flagging issues, and confirming budget availability before signature.
- Provide vendor, study and budget details for purchase order setup in Bill.com.
- Prepare monthly clinical accruals for each vendor using vendor-reported work, unit and milestone data, site activity and Clinical Operations input, for SVP of Finance review.
- Maintain accrual and prepaid schedules supporting accounting journal entries and reclasses, and reconcile them to subsequent invoices.
- Support the annual audit and investor diligence with clear, documented clinical expense support.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
