Senior Director, Medical Capabilities

Arrowhead Pharmaceuticals•Pasadena, CA

3d•$280,000 - $300,000•Onsite

About The Position

Arrowhead Pharmaceuticals is seeking a Senior Director, Medical Capabilities, to lead the team responsible for scientific medical resources, Medical Information, and medical review across the company’s commercialized and pipeline portfolio, primarily in the cardiometabolic therapeutic area. The role sets priorities, establishes reliable processes, and develops colleagues while also contributing hands-on to high-priority deliverables. It ensures Medical Affairs materials and responses are accurate, balanced, current, useful to their intended audiences, and delivered on time. The Senior Director partners with Field Medical, Medical Strategy, Evidence Generation and Dissemination, Clinical Development, Regulatory, Safety, Legal, and Commercial, as appropriate, and reports to the Group Vice President of Medical Affairs. The role leads and develops a globally scoped team across medical resources, Medical Information, and medical review; manages prioritized workplans and scalable content processes; develops scientific and disease-state resources; oversees Medical Information operations and inquiry responses; and provides scientific and medical review within cross-functional governance processes. The position is based in Pasadena, California, with an expectation to work in the office five days a week.

Requirements

Advanced scientific or healthcare degree (PharmD, PhD, MD, DO, or equivalent), or an equivalent combination of education and relevant industry experience.
10 or more years of relevant biopharmaceutical experience, including substantial work in Medical Affairs, Medical Communications, Medical Information, or medical review.
Demonstrated ability to lead and develop colleagues, independently write and review scientific content, and manage multiple complex deliverables to deadlines.
Excellent scientific writing, editing, judgment, and communication skills, with the ability to translate complex evidence into useful materials for different audiences.
Ability to set priorities, meet deadlines, maintain quality under pressure, and communicate progress and risks without prompting.
Collaborative leadership skills, including giving clear direction, holding the team accountable, accepting feedback, and working effectively across functions and regions.
Strong command of clinical data interpretation, scientific literature, references, and requirements for accurate, balanced medical communications.
Knowledgeable and comfortable working in a global and dynamic environment.
Current, valid authorization to work in the country where the role is located.

Nice To Haves

Experience with review and content-management systems.
Experience in launch readiness, rare disease, cardiometabolic medicine, or RNA-targeted therapeutics.

Responsibilities

Lead, coach, and develop a globally scoped team spanning medical resources, Medical Information, and medical review; define roles, standards, capacity, and development plans.
Own an integrated, prioritized workplan with clear owners, due dates, review milestones, and weekly status reporting; identify risks and resolve or escalate barriers.
Develop and maintain scalable processes, training, quality checks, and systems for content intake, authoring, review, and retirement.
Personally create, critically edit, review, and deliver priority work when scientific complexity, timing, or capacity requires it.
Lead development and lifecycle management of cardiometabolic disease-state and product resources, slide decks, field tools, FAQs, training materials, and congress resources for scientific exchange.
Translate clinical, real-world, and published evidence into clear, accurate, appropriately referenced scientific narratives tailored to approved audiences and uses.
Partner with Medical Affairs and other scientific colleagues to identify content gaps, prioritize updates, and roll out resources with practical training and version control.
Personally draft or substantially revise complex and time-sensitive resources, including data updates and launch or pipeline materials.
Lead the Medical Information function and operating model, including intake, triage, response development, fulfillment, documentation, metrics, vendor oversight, and periodic review of standard responses.
Ensure responses to unsolicited medical inquiries are evidence-based, balanced, accurate, timely, and tailored to the question within applicable policies and procedures.
Personally handle complex or escalated scientific inquiries and oversee appropriate handoffs to Safety, Quality, or other functions for adverse events, product complaints, and other reportable information.
Use inquiry trends and feedback to identify evidence gaps, improve standard response documents, and inform Medical Affairs planning and scalability.
Provide timely scientific and medical review within the applicable cross-functional review process, assessing data interpretation, claim support, references, fair balance, and consistency with current evidence and approved materials.
Personally review high-priority or complex materials and provide specific, actionable feedback to support accurate and timely resolution.
Maintain clear review standards, service timelines, documentation, and escalation pathways; partner with Regulatory, Legal, Compliance, and Commercial reviewers while respecting each function’s decision rights.
Oversee content accuracy and currency through scheduled review, change control, and prompt updates when new data or guidance affect existing materials.