Senior Associate Scientist, In Vivo Pharmacology, Neuroscience

Bristol Myers Squibb•Needham, MA

1d•$105,040 - $127,287•Onsite

About The Position

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept. In the role as a Sr. Associate Scientist within In Vivo Pharmacology, the ideal candidate: Performs in vivo pharmacology studies in mice, inclusive of in-life dosing (IV, SC, IP, PO), tissue collection, and tissue processing Performs and/or supports stereotaxic surgery in mice Performs and analyzes PK/PD readouts, such as qPCR/ddPCR, Western blot, immunohistochemistry, and muscle physiology assays Coordinates activities with other team members within the group, across different functions, and with CROs.

Requirements

Bachelor’s Degree
4+ years of academic and / or industry experience
Or
Master’s Degree
2+ years of academic and / or industry experience

Nice To Haves

Extensive mouse handling experience, including common dosing routes, and tissue collection from CNS and peripheral tissues required
Proficiency in standard molecular biology or biochemical assays required
Background in mouse genetics and/or neuroanatomy required
Experience with rodent stereotaxic surgery
Familiarity with in vivo bioluminescence imaging
Experience with mouse breeding or colony management
Immunohistochemistry techniques
Experience working with contract research organization (CROs)
Strong organizational and communication skills
Ability to work independently and as part of a team
Detail-oriented with a commitment to scientific rigor and reproducibility
Adaptability in a fast-paced, collaborative research environment

Responsibilities

Performs in vivo pharmacology studies in mice, inclusive of in-life dosing (IV, SC, IP, PO), tissue collection, and tissue processing
Performs and/or supports stereotaxic surgery in mice
Performs and analyzes PK/PD readouts, such as qPCR/ddPCR, Western blot, immunohistochemistry, and muscle physiology assays
Coordinates activities with other team members within the group, across different functions, and with CROs.

Benefits

wellbeing support
retirement and financial protection benefits
insurance offerings (medical, dental, vision, life and disability)
Flexible Time Off (FTO)
11 paid company holidays each year
160 hours of paid vacation annually for new hires
3 optional holidays
paid sick leave
up to two paid volunteer days per year
summer hours flexibility
leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs
annual Global Shutdown between Christmas Day and New Year's Day