Associate Scientist, In Vivo Pharmacology, Neuroscience

Bristol Myers Squibb•Needham, MA
•$97,120 - $117,688•Onsite

About The Position

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept. In the role as an Associate Scientist within In Vivo Pharmacology, the ideal candidate: Performs in vivo pharmacology studies in mice, inclusive of in-life dosing (IV, SC, IP, PO), tissue collection, and tissue processing Performs and/or supports stereotaxic surgery in mice Performs and analyzes pharmacodynamic (PD) and efficacy readouts, such as ddPCR/qPCR, Western blot, immunohistochemistry, or muscle physiology assays

Requirements

  • Bachelor’s Degree
  • 2+ years of academic and / or industry experience

Nice To Haves

  • Extensive mouse handling experience, including common dosing routes, and tissue collection from CNS and peripheral tissues required
  • Proficiency in standard molecular biology or biochemical assays required
  • Background in mouse genetics and/or neuroanatomy
  • Experience with rodent stereotaxic surgery
  • Familiarity with in vivo bioluminescence imaging
  • Experience with mouse breeding or colony management
  • Experience with immunohistochemistry techniques or muscle physiology assays
  • Strong organizational and communication skills
  • Ability to work independently and as part of a team
  • Detail-oriented with a commitment to scientific rigor and reproducibility
  • Adaptability in a fast-paced, collaborative research environment

Responsibilities

  • Performs in vivo pharmacology studies in mice, inclusive of in-life dosing (IV, SC, IP, PO), tissue collection, and tissue processing
  • Performs and/or supports stereotaxic surgery in mice
  • Performs and analyzes pharmacodynamic (PD) and efficacy readouts, such as ddPCR/qPCR, Western blot, immunohistochemistry, or muscle physiology assays

Benefits

  • wellbeing support
  • retirement and financial protection benefits
  • insurance offerings (medical, dental, vision, life and disability)
  • Flexible Time Off (FTO)
  • 11 paid company holidays
  • 160 hours of paid vacation annually for new hires
  • 3 optional holidays
  • paid sick leave
  • up to two paid volunteer days per year
  • summer hours flexibility
  • leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs
  • annual Global Shutdown between Christmas Day and New Year's Day
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