Scientist/Sr. Scientist, Functional Genomics, Genome Engineering Technology Center

We are seeking a Scientist to join our Genome Engineering Technology Center at Arc Institute. This role will involve supporting the development of cutting-edge functional genomics approaches focused on the high-throughput interrogation of mammalian genomes, transcriptomes, and epigenomes. The ideal candidate will have a passion for technology development and a proven track record in developing high-throughput CRISPR screens. This is an excellent opportunity for a highly motivated scientist interested in the intersection of basic research and biotech product development.

• Design and run pooled functional genomics screens to prototype new technology and generate key data sets for technology development
• Work closely with core academic labs on collaborative projects
• Support the development of cutting-edge functional genomics approaches focused on the high-throughput interrogation of mammalian genomes, transcriptomes, and epigenomes with rich multi-omic readouts
• Collaborate with scientists from other teams, labs, and scientific domains
• Develop high-throughput CRISPR screens in mammalian cell culture or animal models
• Create technology and platforms that are scalable and useful in many different scientific application areas
• Optimize processes to ensure efficiency and speed in scientific research
• Contribute to the understanding and treatment of complex genetic diseases through technology development
• Conduct curiosity-driven basic science and technology development to understand and treat complex human diseases
• Provide first-class support operationally, financially, and scientifically to enable scientists to pursue long-term high-risk, high-reward research
• Foster a culture focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.

• Experience in developing high-throughput CRISPR screens in mammalian cell culture or animal models
• Passion for technology development in the field of functional genomics
• Proven track record in developing cutting-edge functional genomics approaches
• Expertise in the high-throughput interrogation of mammalian genomes, transcriptomes, and epigenomes
• Ability to work collaboratively with scientists from different teams, labs, and scientific domains
• Strong skills in designing and running pooled functional genomics screens
• Proficiency in creating scalable and useful technology and platforms for various scientific application areas
• Strong optimization skills to ensure efficiency and accuracy in research processes

• Fully funded research groups for Core Investigators
• Development and deployment of experimental and computational technologies
• First-class support operationally, financially, and scientifically
• Focused on scientific curiosity, commitment to truth, broad ambition, and selfless collaboration
• Competitive title and compensation relative to experience level and background
• Opportunity to work on cutting-edge functional genomics approaches
• Collaboration with scientists from different teams, labs, and scientific domains
• Opportunity to create scalable and useful technology and platforms
• Emphasis on efficiency and optimization
• Design and run functional genomics screens
• Collaborative projects with core academic labs
• Technical input to technology development roadmap
• Project management responsibilities
• Opportunities to report progress and present data in internal and external meetings
• Base salary range of $112,500 to $148,500
• Eligibility for annual discretionary bonus