Scientist, In Vivo Pharmacology (Night Shift)

Capable Labs • San Francisco, CA

3d • Onsite

About The Position

We are a vibrant and intensely mission-driven team in San Francisco, comprising members from MIT, Harvard Medical School, Roche, ETH, and Dana-Farber. We value speed and rigor, coupled with excitement, drive, and a strong work ethic. In an early-stage environment, we value people who can bring clarity to open-ended problems, take ownership of the next steps, and follow through with energy. Capable Labs is a place for ambitious, high-integrity people who want to become dramatically better. You will be surrounded by people who care intensely about the work, get close feedback from the people making scientific and company-defining decisions, and have room to own increasingly important problems. We believe excellent work should be met with meaningful reward, ownership, and trust. Responsibility is earned through contribution, not title alone: anyone who demonstrates the judgment, rigor, and follow-through to move important work forward can earn meaningful scope. About the Role You will execute mouse studies on a dedicated night-shift schedule, enabling overnight dosing, collections, procedures, and continuous study coverage. You will perform in vivo work carefully and independently, organize samples and data, support specialized procedures including EEG studies, and provide complete handoffs that allow the day team to interpret results and move quickly.

Requirements

• Able and willing to work the designated night-shift schedule reliably and operate independently when needed.
• Hands-on experience running mouse studies in biotech, pharma, academia, or a closely related setting.
• Comfort with common dosing routes, animal handling, sample collection, accurate records, and protocol-compliant in vivo execution.
• Sound judgment, careful attention to animal welfare and data quality, and a habit of documenting and communicating issues early.
• The ability to create clean, useful handoffs for scientists interpreting the study and planning what comes next.

Nice To Haves

• Experience with surgeries, EEG procedures, intranasal dosing, or other specialized methods is helpful; you do not need experience with every procedure listed.

Responsibilities

• Run overnight portions of mouse studies evaluating therapeutic candidates for safety and effectiveness.
• Dose mice using routes such as IP, IV, SC, PO, and intranasal administration in accordance with study designs, protocols, and your training.
• Collect blood and disease-relevant tissues; prepare, label, track, process, and store samples correctly for downstream analysis.
• Perform or support surgeries and specialized in vivo procedures, including EEG surgeries and EEG-study execution where required.
• Monitor study conduct and animal welfare, document observations and deviations, and make or escalate protocol-based decisions during overnight hours.
• Perform routine vivarium duties as needed, including cage care, bedding changes, supply restocking, and animal-health monitoring.
• Organize dosing, procedure, sample, and animal-health data so that the study record is complete and interpretable.
• Provide clear morning handoffs covering completed work, results, issues, samples, and recommended follow-up.

Benefits

• Generous equity options
• $500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools that help you perform at your best.
• Medical, dental, and vision coverage options, with Capable covering 100% of the base policy.
• HSA, FSA, and 401K plans.
• Healthy dinners with the team are provided daily.
• Visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: No Education Listed