Scientist 1, In Vitro Pharmacology

Crinetics Pharmaceuticals • San Diego, CA

6d • Onsite

About The Position

The Scientist 1, In Vitro role works closely with colleagues within the Biology, Chemistry, and Preclinical Development teams to evaluate new drug modalities by performing mechanistic studies and participate in discovery and translational efforts aimed at identifying and characterizing novel targeted therapeutic targets. This role works in a dynamic environment to help advance programs from discovery into development, as part of a multidisciplinary team.

Requirements

• Ph.D. in Biology, Behavioral Pharmacology, Physiology, Neuroscience, or related discipline with research experience in disease-related biology.
• Applicants with BS or MS degrees may apply but must demonstrate a minimum of 8 to 10 years of significant and relevant experience in pharmaceutical or life sciences industry.
• Strong cell culture expertise with proven experience in cell line development
• Experience with basic molecular biology techniques using DNA, RNA, and protein.
• Strong knowledge of molecular biology techniques to support cell line generation.
• Detail-oriented, with excellent organization and record-keeping skills.
• Capable of working both independently with minimal oversight and in a collaborative environment.
• Outstanding written and oral presentation capabilities,
• Software knowledge in Windows, MS Office (Outlook, Word, Excel, PowerPoint, SharePoint, Teams), GraphPad Prism, among others as required.

Nice To Haves

• Experience in RNAi (siRNA, miRNA, ASOs) design and delivery.
• Experience in developing cancer, immunology, in vitro cell-based assays

Responsibilities

• Develop and maintain multiple cell lines independently.
• Implement excellent aseptic technique required for primary cell culture.
• Design, optimize, and validate pharmacology assays.
• Perform, analyze, and interpret assays independently.
• Maintain electronic laboratory notebooks in a timely and accurate manner.
• Write standard operating protocols.
• Participate in cross-functional drug discovery teams and interact with cross-functional groups effectively.
• Provide guidance and training to junior scientists.
• Interpret and present data and findings to cross-functional teams and leadership.
• Support the organization in maintaining a work environment focused on scientific integrity and quality, and one that fosters learning, open communication, collaboration, and teamwork.
• Other duties as assigned.

Benefits

• discretionary annual target bonus
• stock options
• ESPP
• 401k match
• top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance
• 20 days of PTO
• 10 paid holidays
• a winter company shutdown

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree