Scientific Director, Bioconjugation Development
About The Position
Neurocrine Biosciences is a leading biopharmaceutical company dedicated to discovering, developing, and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine, and immunological disorders. This leadership role sets the long-term scientific vision for bioconjugation development, shaping portfolio strategy for next-generation antibody-drug conjugates (ADCs), antibody-peptide conjugates (APCs), antibody-oligonucleotide conjugates (AOCs), and related targeted delivery platforms. The role drives innovation in conjugation technologies, linker-payload design, manufacturability, and product development, while strengthening external scientific engagement and ensuring deep product understanding, CMC excellence, and regulatory credibility remain central to organizational decision-making. By guiding functional development and aligning bioconjugation strategy with business priorities, this position will have a broad impact on both current programs and future platform development.
Requirements
- BS/BA in chemistry, biochemistry, biology, or similar scientific discipline and 12+ years of relevant experience OR MS/MA in chemistry, biochemistry, biology, or similar scientific discipline and 10+ years of relevant experience OR PhD in chemistry, biochemistry, biology, or similar scientific discipline or equivalent and 8+ years of relevant experience
- Expert in bioconjugate development strategies including site-specific conjugation technologies, DAR control, and late stage/commercial bioconjugate development
- Extensive experience with bioconjugate manufacturing, technology transfer, and commercialization
- Comprehensive regulatory knowledge for bioconjugate therapeutics
- Advanced cross-functional leadership across discovery, CMC, quality, regulatory, and external partner organizations
- Guides enterprise-level bioconjugation development initiatives and platform strategies
- Demonstrates strategic execution excellence in advancing complex programs
- Drives the strategic direction of the functional area
- Broad scientific mastery guiding organizational leadership
- Widely recognized scientific authority in bioconjugation, conjugation chemistry, or related disciplines
- Deep understanding of business strategy and corporate objectives
- Communicates scientific direction across the organization
- Translates strategy into actionable plans
- Leads multiple teams effectively
- Mentors mid-level leaders
- Exceptional communication and influence skills
- Develops long-term organizational vision
- Strong executive-level project leadership
- Shapes organizational practices strategically
- Influences external stakeholders
Responsibilities
- Lead teams driving strategic bioconjugation development initiatives across the portfolio
- Establish long-term scientific vision for ADC, APC, AOC, and emerging bioconjugate modalities, influencing enterprise strategy
- Lead design and execution of departmental strategies and policies for bioconjugate process development
- Maintain strategic oversight of functional deliverables
- Drive cross-functional initiatives with department-wide impact across discovery, manufacturing, quality, and regulatory functions
- Develop and oversee enterprise-level risk management strategies for bioconjugate products, platforms, and manufacturing processes
- Manage external manufacturing partnerships strategically
- Lead innovation initiatives across bioconjugation technologies, linker chemistries, payloads, and targeted delivery platforms
- Guide strategic direction of multiple development programs from candidate selection through commercialization
- Influence enterprise-level decision making
- Develop functional capabilities and leadership talent in bioconjugation development
- Perform other duties as assigned
Benefits
- Annual bonus
- Equity based long term incentive program
- Retirement savings plan (with company match)
- Paid vacation, holiday and personal days
- Paid caregiver/parental and medical leave
- Health benefits to include medical, prescription drug, dental and vision coverage
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
