Scientific Director, Bioconjugation Development

Neurocrine Biosciences • San Diego, CA

7d

About The Position

Set the long-term scientific vision for bioconjugation development, shaping portfolio strategy for next-generation antibody-drug conjugates (ADCs), antibody-peptide conjugates (APCs), antibody-oligonucleotide conjugates (AOCs), and related targeted delivery platforms. This leadership role drives innovation in conjugation technologies, linker-payload design, manufacturability, and product development, while strengthening external scientific engagement and ensuring deep product understanding, CMC excellence, and regulatory credibility remain central to organizational decision-making. By guiding functional development and aligning bioconjugation strategy with business priorities, you will have broad impact on both current programs and future platform development.

Requirements

• BS/BA in chemistry, biochemistry, biology, or similar scientific discipline and 12+ years of relevant experience OR MS/MA in chemistry, biochemistry, biology, or similar scientific discipline and 10+ years of relevant experience OR PhD in chemistry, biochemistry, biology, or similar scientific discipline or equivalent and 8+ years of relevant experience
• Expert in bioconjugate development strategies including site-specific conjugation technologies, DAR control, and late stage/commercial bioconjugate development
• Extensive experience with bioconjugate manufacturing, technology transfer, and commercialization
• Comprehensive regulatory knowledge for bioconjugate therapeutics
• Advanced cross-functional leadership across discovery, CMC, quality, regulatory, and external partner organizations
• Guides enterprise-level bioconjugation development initiatives and platform strategies
• Demonstrates strategic execution excellence in advancing complex programs
• Drives the strategic direction of the functional area
• Broad scientific mastery guiding organizational leadership
• Widely recognized scientific authority in bioconjugation, conjugation chemistry, or related disciplines
• Deep understanding of business strategy and corporate objectives
• Communicates scientific direction across the organization
• Translates strategy into actionable plans
• Leads multiple teams effectively
• Mentors mid-level leaders
• Exceptional communication and influence skills
• Develops long-term organizational vision
• Strong executive-level project leadership
• Shapes organizational practices strategically
• Influences external stakeholders

Responsibilities

• Lead teams driving strategic bioconjugation development initiatives across the portfolio
• Establish long-term scientific vision for ADC, APC, AOC, and emerging bioconjugate modalities, influencing enterprise strategy
• Lead design and execution of departmental strategies and policies for bioconjugate process development
• Maintain strategic oversight of functional deliverables
• Drive cross-functional initiatives with department-wide impact across discovery, manufacturing, quality, and regulatory functions
• Develop and oversee enterprise-level risk management strategies for bioconjugate products, platforms, and manufacturing processes
• Manage external manufacturing partnerships strategically
• Lead innovation initiatives across bioconjugation technologies, linker chemistries, payloads, and targeted delivery platforms
• Guide strategic direction of multiple development programs from candidate selection through commercialization
• Influence enterprise-level decision making
• Develop functional capabilities and leadership talent in bioconjugation development
• Perform other duties as assigned

Benefits

• retirement savings plan (with company match)
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree