Research Specialist C
About The Position
The Penn-CHOP Lung Biology Institute in the Department of Medicine at the University of Pennsylvania is seeking to hire a highly skilled histopathologist as a Research Specialist C to join a dynamic and cutting-edge research team exploring regenerative lung biology. The Research Specialist C position will be responsible for working independently to perform precision tissue processing via cryostat, vibratome and microtome to produce extremely thin and uniform histological slices, perform complex histological techniques including hematoxylin and eosin staining, novel antibody staining/quality control testing, antigen retrieval processes, in situ hybridization, RNAScope, 3D spatial techniques such as 10XVisium and other emerging imaging techniques. The candidate will also be expected to train and supervise laboratory stuff on histopathology protocols and maintain large histology databases for the institute. They will also be expected to interact daily with senior researchers to jointly produce publication quality staining and images, contribute to the development of new techniques, generate data for top tier research publications and grant applications, assist with general laboratory maintenance duties and be given the opportunity to accomplish independent research projects and advance their own education.
Requirements
- Bachelor of Science and 3 to 5 years of experience or equivalent combination of education and experience is required.
Responsibilities
- Perform tissue paraffin and agarose embedding and perform various sectioning techniques such as Microtome, Cryostat and Vibratome and Compresstome tissue sectioning (microns thick) of human and mouse samples and perform immunohistochemistry, immunofluorescence and affinity based chemical reactions on these slides for downstream antigen analyses.
- Perform highly sensitive methodologies to quantitate RNA transcript levels (RNAScope), optimizing RNA probes across multiple transcripts and combine with traditional immunohistochemistry techniques.
- Perform 3D spatial transcriptomics and other 3D histology next generation sequencing platforms.
- Collaborate with senior lab members to discuss projects and results, develop independent long term project goals, assist with the generation and preparation of data for the submission of manuscripts and grants.
- Ensure that paraffin embedded sections are carefully organized and catalogued for human and mouse biorepository and databases for antibodies and all experimental conditions and results are recorded and maintained.
- Other duties and responsibilities as assigned.
Benefits
- excellent healthcare
- tuition benefits for employees and their families
- generous retirement benefits
- wide variety of professional development opportunities
- supportive work and family benefits
- wealth of health and wellness programs and resources
- comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits
- flexible spending accounts
- tuition assistance here at Penn
- tuition assistance at other institutions for dependent children
- generous retirement plans
- substantial amount of time away from work
- long-term care insurance
- wide variety of programs and resources to help you care for your health, your family, and your work-life balance
- array of resources to help you advance yourself personally and professionally
- access to a wide range of University resources as well as cultural and recreational activities
- free admission and memberships to Penn arts and cultural centers and museums
- substantial savings on other goods and services
- flexible work options
- forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia
- reimbursement for qualified expenses in connection with the legal adoption of an eligible child
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
