Research Fellow - Cancer Biology

American Addiction CentersCharlotte, NC
$31 - $46Onsite

About The Position

An opportunity is available for a Postdoctoral Research Fellow in the laboratory of Dr. Wa Xian and Dr. Frank McKeon at Wake Forest University, North Carolina. Candidates should have a Ph.D., demonstrated experience in synthetic organic/medicinal chemistry with emphasis on heterocyclic compound chemistry, and an ability to work independently. A background in medicinal chemistry and drug discovery with experience of parallel synthesis and purification methods is required. Some experience in molecular modeling and/or protein-inhibitor visualization is a plus. Qualified candidates are encouraged to apply and attach a cover letter and curriculum vitae. Candidates will be requested to provide names and contact information for two references. Review of applications will continue until the position is filled.

Requirements

  • Ph.D. in Medicinal Chemistry or Organic Chemistry with years academic experience.
  • Strong hands-on experience in small-molecule design, synthesis, purification, and characterization.
  • Proficiency with LC/MS, NMR, analytical HPLC, and prep HPLC.
  • Required proficiency in using SciFinder, Reaxys, Chemdraw, etc.
  • Effective oral and written communication skills; contributed to internal reports, technical documentation, or peer-reviewed publications.

Nice To Haves

  • Some experience in molecular modeling and/or protein-inhibitor visualization is a plus.

Responsibilities

  • Independently execute multi-step organic syntheses, purify, and characterize small molecules.
  • Apply solid-phase synthesis and bioconjugation chemistry to complex molecules.
  • Partner with cross-functional teams to interpret SAR and guide compound design.
  • Document results, maintain accurate digital records, and adhere to EHS and laboratory best practices.

Benefits

  • Paid Time Off programs
  • medical, dental, vision, life, and Short- and Long-Term Disability
  • Flexible Spending Accounts for eligible health care and dependent care expenses
  • adoption assistance and paid parental leave
  • Defined contribution retirement plans with employer match and other financial wellness programs
  • Educational Assistance Program
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