Research Fellow - Cancer Biology

Advocate Health and Hospitals Corporation • Charlotte, NC

23h • Onsite

About The Position

An opportunity is available for a Postdoctoral Research Fellow in the laboratory of Dr. Wa Xian and Dr. Frank McKeon at Wake Forest University, North Carolina. Candidates should have a Ph.D., demonstrated experience in synthetic organic/medicinal chemistry with emphasis on heterocyclic compound chemistry, and an ability to work independently. A background in medicinal chemistry and drug discovery with experience of parallel synthesis and purification methods is required. Some experience in molecular modeling and/or protein-inhibitor visualization is a plus. Qualified candidates are encouraged to apply and attach a cover letter and curriculum vitae. Candidates will be requested to provide names and contact information for two references. Review of applications will continue until the position is filled.

Requirements

• Ph.D. in Medicinal Chemistry or Organic Chemistry with years academic experience.
• Strong hands-on experience in small-molecule design, synthesis, purification, and characterization.
• Proficiency with LC/MS, NMR, analytical HPLC, and prep HPLC.
• Required proficiency in using SciFinder, Reaxys, Chemdraw, etc.
• Effective oral and written communication skills; contributed to internal reports, technical documentation, or peer-reviewed publications.

Nice To Haves

• Some experience in molecular modeling and/or protein-inhibitor visualization is a plus.

Responsibilities

• Independently execute multi-step organic syntheses, purify, and characterize small molecules.
• Apply solid-phase synthesis and bioconjugation chemistry to complex molecules.
• Partner with cross-functional teams to interpret SAR and guide compound design.
• Document results, maintain accurate digital records, and adhere to EHS and laboratory best practices.

Benefits

• Paid Time Off programs
• medical, dental, vision, life, and Short- and Long-Term Disability
• Flexible Spending Accounts for eligible health care and dependent care expenses
• adoption assistance and paid parental leave
• Defined contribution retirement plans with employer match and other financial wellness programs
• Educational Assistance Program

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree