Serif Biomedicines: Protein Engineering Co-Op
About The Position
This position is open exclusively to current Northeastern University Co-Op students. The work period is from January 2027 to June 2027. This is a full-time, 40 hours per week position with 5 days in office. Serif Biomedicines, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases. Serif Biomedicines was founded by Flagship Pioneering's venture creation engine that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Flagship Pioneering Co-Op Program offers enrichment sessions, a dedicated professional development track, and a mentor. As a member of our protein engineering team, you’ll work at the intersection of computational protein design and wet-lab experimental validation to help design, test, and refine novel proteins.
Requirements
- Pursuing a MS in Molecular Biology, Cell Biology, Bioengineering, Biochemistry, or a related field.
- Hands-on experience with core wet-lab techniques: PCR, molecular cloning, flow cytometry
- Basic proficiency in a programming language used for data analysis (e.g., Python, R), and comfort working in command-line environments.
- Experience with DNA sequence analysis.
- Strong organizational skills, attention to detail, and clear written/verbal communication
Nice To Haves
- Familiarity with ML architectures for protein engineering and common models (e.g., AlphaFold, RFDiffusion) a plus.
Responsibilities
- Apply state-of-the-art ML models of protein sequence and structure to engineer novel proteins with desired functions.
- Construct DNA libraries and transform them into yeast for functional analysis with FACS and flow cytometry.
- Coordinate biophysical characterization of protein binders with third-party vendors.
- Analyze and clearly communicate experimental results; iterate protocols in collaboration with experienced scientists.
Benefits
- Compensation reflects the real work you take on.
- Retirement benefits may be available after completing a set number of hours.
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What This Job Offers
Job Type
Full-time
Career Level
Intern
