Serif Biomedicines: Molecular Biology Co-Op

Flagship Pioneering•Cambridge, MA

5d•Onsite

About The Position

This position is open exclusively to current Northeastern University Co-Op students. Work Period: January 2027 to June 2027. This is a full-time, 40 hours per week position with 5 days in office. At Serif Biomedicines, we push the boundaries of DNA design, precise cloning, and cell-based engineering to accelerate the discovery and development of transformative therapeutics and diagnostics. Serif Biomedicines was founded by Flagship Pioneering's venture creation engine that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Flagship has been recognized twice on FORTUNE’s “Change the World” list and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Welcome to Flagship Pioneering Co-Op Program for the cohort dreaming big and taking courageous leaps. You'll join fellow peers across our ecosystem of companies and learning firsthand how we build first-in-category companies. You’ll have access to enrichment sessions, a dedicated professional development track, and a mentor that help guide you toward your next step. By the end, you will carry on a meaningful project outcome, a genuine network, and a front-row view of how Flagship pioneer new ventures that change the world. As a member of our molecular biology team, you’ll work at the forefront of hands-on research from constructing DNA plasmids to analyzing cell phenotypes and protein expression. Embark on an exhilarating journey with Serif Biomedicines, where your contributions at the bench will accelerate breakthrough molecular biology and shape what’s possible in biotech.

Requirements

Highly motivated and enthusiastic co-op students eager to dive into fast-paced, impactful bench science.
Curious problem solvers who learn new techniques quickly and think creatively.
Individuals with a strong foundation in molecular biology and cell culture.
Pursuing a MS in Molecular Biology, Cell Biology, Bioengineering, Biochemistry, or a related field.
Hands-on experience with core techniques: miniprep/midiprep, PCR, agarose gel electrophoresis, restriction enzyme digests, ligation, and DNA purification.
Strong organizational skills, attention to detail, and clear written/verbal communication.

Nice To Haves

Experience with synthetic biology, genome engineering, or assay development is a plus.

Responsibilities

Design, build, and QC DNA constructs using restriction cloning, Gibson/Golden Gate assembly, and PCR.
Run agarose DNA gels to analyze PCR products and digests; perform gel extraction and DNA purification.
Set up restriction enzyme digests and ligations; optimize reaction conditions and troubleshoot cloning workflows.
Perform core molecular and cell biology tasks, including DNA/RNA extraction, qPCR/RT-qPCR, transfection/transduction, and clonal line generation.
Analyze and clearly communicate experimental results; iterate protocols in collaboration with experienced scientists.