Principal Research Associate, Multiplex Immunohistochemistry & Digital Pathology

Genmab • Princeton, TX

2d • Onsite

About The Position

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees. Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. This role is within the immunohistochemistry laboratory, as part of an international Pathology team embedded within the Precision Medicine group based in Princeton, New Jersey. In this role you will help build a state-of-the-art histology and immunohistochemistry team to support a variety of discovery, pre-clinical and clinical programs. Knowledge of Digital Pathology is recommended for this role.

Requirements

• Bachelor’s degree in biomedical science with an interest/experience in histology and immunohistochemistry assay development.
• Minimum of 5 years Research experience
• Experience managing human tissues and working with Laboratory Information Management Systems (LIMS).
• Excellent written and verbal communication skills and experience with Excel and PowerPoint.
• Positive and open mindset and willingness to work in multidisciplinary teams in close collaboration with pathologists and other scientists.

Nice To Haves

• Multiplex immunohistochemistry staining on Leica Bond and Roche Discovery/Benchmark Ultra Plus platforms are a plus.
• Eligibility for American Society for Clinical Pathology (ASCP) certification for Histotechnician (HT) or Histotechnologist (HTL) desired but not required.
• Understanding and experience with CAP Accreditation requirements is a plus.
• Knowledge of pre-clinical tissue processing and biomarker development is desired but not required.

Responsibilities

• Process, embed, and section tissue blocks (paraffin) for human and tissues.
• Perform histologic tissue stains such as Hematoxylin & Eosin (H&E) and run immunohistochemistry (IHC) assays for single-plex chromogenic and fluorescence, as well as multiplex IHC and IF using our automated platforms (Leica Bond, Ventana Discovery Ultra, Ventana Benchmark Ultra Plus).
• Run in situ hybridization (ISH) assays using RNA Scope and Base scope probes, in single and multiple channels, mainly on the Leica Bond platform.
• Scan microscopic slides using standard bright field and fluorescence scanners as needed and perform basic image analysis using Halo, Visio pharm, Leica AT2, Leica GT450.
• Perform digital pathology image analysis on scanned stained slides and develop algorithms to evaluate data.
• Help manage a human tissue database and downstream lab processes using a Laboratory Information Management System (LabVantage), and a digital image database.

Benefits

• 401(k) Plan: 100% match on the first 6% of contributions
• Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance
• Voluntary Plans: Critical illness, accident, and hospital indemnity insurance
• Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave
• Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support
• Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses

What This Job Offers

• Job Type: Full-time
• Career Level: Principal