Postdoctoral Fellow-MSH-30035-404

Mount Sinai Health System • New York, NY

1d • Onsite

About The Position

The Postdoctoral Fellow will investigate activity-dependent mechanisms of histone monoaminylation, a novel mark discovered by the Maze lab and mediated by transglutaminase enzymes. The research aims to determine molecular mechanisms contributing to activity-dependent histone monoaminylation in the central nervous system. The work will examine transglutaminase nuclear shuttling, complex binding, and recruitment to chromatin, as well as histone monoaminylation deposition, removal, and exchange. Research will use biochemical, molecular, genomic, proteomic, and behavioral approaches. The position is in the Neuroscience Department at the Icahn School of Medicine at Mount Sinai, with a physical work location at Hess CSM, 1470 Madison Avenue, S9-201, New York, NY 10029. The role is supervised by Ian Maze, PhD.

Requirements

• PhD or equivalent.
• No years of postdoctoral experience are required.

Responsibilities

• Investigate activity-dependent mechanisms of histone monoaminylation in the central nervous system.
• Use biochemical, molecular, genomic, proteomic, and behavioral approaches to study transglutaminase nuclear shuttling, complex binding, and recruitment to chromatin.
• Investigate mechanisms of histone monoaminylation deposition, removal, and exchange.
• Determine molecular mechanisms contributing to activity-dependent histone monoaminylation.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree