Postdoctoral Associate - Disney Lab

University of Florida • Palm Beach, FL

3d • Onsite

About The Position

Effective immediately, the Disney group in the Department of Chemistry at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology is seeking to hire a Postdoctoral Associate in RNA Chemical Biology. The Disney group is a chemical biology laboratory focused on developing rational approaches to design highly selective therapeutics from only genome sequence. Known for its prolific output and pioneering research culture, the group has furthered advancements in annotating RNA structure from sequence alongside several novel technologies created in-house. The laboratory’s targeting of RNA by small molecules, an ambitious and highly focused enterprise in pursuit of chemical probe and lead medicine development, is summarized in Nature Reviews Drug Discovery (2023) 618(7963): 169–179. The Disney group is highly committed to each individual’s professional development during his or her time in the lab. A high impact research project and training plan to support the achievement of short-term as well as long-term career goals is customized for each student.

Requirements

• Completed a relevant Ph.D. degree in structural biology, chemical biology, or organic/medicinal chemistry.
• Strong academic track-record.
• High-impact publication list.
• Team-player mentality.
• Interest in targeting the RNA world.
• Willingness to learn new methods.

Nice To Haves

• Strong skills in RNA biology techniques.
• Strong skills in molecular biology.
• Strong skills in biochemical methods.
• Previous experience with RNA-seq data analysis.
• Previous experience with DNA encoded library design and screening.
• Previous experience with structure-based design.

Responsibilities

• Conduct research in RNA Chemical Biology.
• Develop rational approaches to design highly selective therapeutics from genome sequence.
• Annotate RNA structure from sequence.
• Develop novel technologies.
• Target RNA by small molecules for chemical probe and lead medicine development.
• Study disease mediated by RNA repeat expansions that cause genetically defined ALS and dementia.
• Develop targeted RNA degradation and related technologies.
• Develop precision targeted therapeutics for difficult-to-treat cancers and other diseases.
• Participate in a high impact research project.
• Engage in a training plan to support career goals.

Benefits

• Commensurate with experience.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree