Postdoctoral Research Associate - Gottschalk lab
About The Position
A fully supported postdoctoral fellowship in the Gottschalk Laboratory, led by Dr. Gottschalk, focused on developing immune-based therapies for pediatric solid and brain tumors. The research aims to develop T-cell-based therapies using genetic engineering to make immune cells cancer-specific and improve their effector function. Genetically modified immune cells will be studied in preclinical models, with emphasis on their interactions with tumor cells, the tumor microenvironment, and resident immune cells. The ultimate goal is to translate these approaches into early-phase clinical testing. The successful candidate will join a collaborative research group that values respect and collaboration. The laboratory also emphasizes members’ success and professional growth.
Requirements
- A Ph.D. or equivalent degree in molecular biology, cell biology, genetics, genomics, immunology, or a related area.
- A strong publication record.
- Excellent communication skills.
- A strong background in immunology and cell biology, with an emphasis on cellular immunology and genetic manipulation of mammalian cells.
Nice To Haves
- Experience generating and evaluating human or murine immune cells.
- Experience with gene editing.
- Experience with single-cell transcriptomics.
- Experience with flow cytometry.
- Experience with murine solid tumor models.
Responsibilities
- Develop T-cell-based therapies for pediatric solid and brain tumors.
- Use genetic engineering approaches to make immune cells cancer-specific and improve their effector function.
- Study genetically modified immune cells in preclinical models, including their interactions with tumor cells, the tumor microenvironment, and resident immune cells.
- Contribute to research intended to translate therapeutic approaches into early-phase clinical testing.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
