Postdoctoral Research Associate - Gottschalk lab

St. Jude Children's Research Hospital•Memphis, TN

About The Position

The Gottschalk Laboratory is seeking a highly motivated and creative candidate for a fully supported postdoctoral fellowship developing immune-based therapies. The research project aims to develop T-cell-based therapies for pediatric solid and brain tumors. Studies use genetic engineering to make immune cells cancer-specific and improve their effector function. Genetically modified immune cells are studied in preclinical models, with emphasis on their interactions with tumor cells, the tumor microenvironment, and resident immune cells. The ultimate goal is to translate these approaches into early Phase clinical testing. The postdoctoral fellow will join a collaborative research group committed to a culture of respect and collaboration. The laboratory also prioritizes the success and professional growth of its members.

Requirements

A Ph.D. or equivalent degree in molecular biology, cell biology, genetics, genomics, immunology, or a related area.
A strong publication record.
Excellent communication skills.
A strong immunology and cell biology background, with an emphasis on cellular immunology and genetic manipulation of mammalian cells.

Nice To Haves

Experience generating and evaluating human or murine immune cells.
Experience with gene editing.
Experience with single cell transcriptomics.
Experience with flow cytometry.
Experience with murine solid tumor models.

Responsibilities

Develop immune-based therapies, including T-cell-based therapies for pediatric solid and brain tumors.
Use genetic engineering approaches to make immune cells cancer-specific and improve their effector function.
Study genetically modified immune cells in preclinical models, focusing on interactions with tumor cells, the tumor microenvironment, and resident immune cells.
Contribute to research intended to translate these approaches into early Phase clinical testing.