Post-Doctoral Research Fellow-Center for Psychiatric Genetics

Endeavor Health • Evanston, IL

4d • $63,480 - $77,076 • Onsite

About The Position

Endeavor Health Research Institute’s Center for Psychiatric Genetics, academically affiliated with the University of Chicago, is seeking a self-motivated postdoctoral fellow. The lab uses patient-specific induced pluripotent stem cell (iPSC)-derived neurons and brain organoid models to study the molecular and neurobiological basis of neuropsychiatric and neurodegenerative disorders. The NIH grant-funded position focuses on developing brain organoid models carrying disease risk alleles to study molecular and cellular phenotypes relevant to neurodevelopmental and/or neurodegenerative disorders, with opportunities to participate in single-cell ATAC-seq/RNA-seq experiments and analyses. Laboratory methods include iPSC neural modeling, single-cell RNA-seq and ATAC-seq, CRISPR/Cas9 gene editing, CRISPRi/a gene perturbation, and scaled morphological and electrophysiological analyses of neurons and brain organoids.

The fellow will take a lead role in NIH-funded projects and work independently under the supervision of the PI, a Professor at the University of Chicago. The position is full-time, benefits-eligible, and onsite in Evanston, Illinois, during standard Monday–Friday business hours. Compensation is determined by NIH Salary Guidelines and is listed as $63,480–$77,076.

Endeavor Health describes itself as a fully integrated healthcare delivery system serving more than 4.2 million residents across six northeast Illinois counties. It has more than 25,000 team members, more than 6,000 physicians, more than 300 ambulatory locations, and eight acute care hospitals. The organization states that it encourages employees to pursue career goals and professional growth and is committed to a culture of connection and belonging. Reasonable accommodations are available to individuals with disabilities.

Requirements

• PhD or MD in a science field.
• Excellent communication skills.

Nice To Haves

• Background in molecular or cellular biology, neuroscience, or functional genomics.
• Experience with neuroscience research, especially iPSC culture and organoid differentiation.

Responsibilities

• Take a lead in work involved in NIH-funded projects.
• Work independently under the supervision of the PI.
• Develop brain organoid models carrying disease risk alleles to study relevant molecular and cellular phenotypes.
• Participate in single-cell ATAC-seq/RNA-seq experiments and analyses.
• Prepare scientific manuscripts for publication.
• Develop scientific proposals to apply for fellowships.
• Identify problems that may adversely affect experiments or reporting of results, take corrective action, or notify appropriate supervisory personnel.
• Comply with Endeavor Health research guidelines and follow IRB regulations and local, state, and federal research regulations.
• Assist with submission of research applications, revisions, and periodic progress reports.

Benefits

• Premium pay such as shift, on-call, and holiday pay, based on the employee’s job and eligibility.
• Incentive pay for select positions.
• Opportunity for annual increases based on performance.
• Career pathways to promote professional growth and development.
• Medical, dental, pet, and vision options.
• Tuition reimbursement.
• Free parking.
• Wellness Program Savings Plan.
• Health Savings Account options.
• Retirement options with company match.
• Paid time off and holiday pay.
• Community involvement opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree