Post-Doctoral Research Fellow-Center for Psychiatric Genetics

Endeavor Health • Evanston, IL

3d • Onsite

About The Position

Endeavor Health Research Institute’s Center for Psychiatric Genetics is seeking a self-motivated postdoctoral fellow. The center is academically affiliated with the University of Chicago, and the role reports directly to a principal investigator who is a University of Chicago professor. The lab uses patient-specific induced pluripotent stem cell (iPSC)-derived neurons and brain organoid models to study the molecular and neurobiological basis of neuropsychiatric and neurodegenerative disorders. The position is NIH grant-funded and will take a lead in developing brain organoid models carrying disease risk alleles to investigate molecular and cellular phenotypes relevant to neurodevelopmental and/or neurodegenerative disorders. The fellow may also participate in single-cell ATAC-seq and RNA-seq experiments and analyses.

Laboratory research includes iPSC neural modeling, single-cell RNA-seq and ATAC-seq, CRISPR/Cas9 gene editing, CRISPRi/a gene perturbation, and scaled morphological and electrophysiological analyses of neurons and brain organoids. This is a full-time, benefits-eligible, onsite position in Evanston, Illinois, with standard business hours Monday through Friday. Compensation is determined according to NIH salary guidelines, with a stated range of $63,480–$77,076.

Endeavor Health describes itself as a fully integrated healthcare delivery system serving more than 4.2 million residents across six northeast Illinois counties. The organization reports more than 25,000 team members, more than 6,000 physicians, over 300 ambulatory locations, and eight acute care hospitals. It emphasizes professional growth, connection and belonging, and providing safe, seamless, personal care. Endeavor Health is an equal opportunity employer and provides reasonable accommodation to individuals with disabilities.

Requirements

• PhD or MD in a science field.
• Excellent communication skills.

Nice To Haves

• Background in molecular or cellular biology, neuroscience, or functional genomics.
• Experience with neuroscience research, especially iPSC culture and organoid differentiation.

Responsibilities

• Take a lead in work involved in NIH-funded projects.
• Develop brain organoid models carrying disease risk alleles to study disease-relevant molecular and cellular phenotypes.
• Work independently under the supervision of the principal investigator.
• Prepare scientific manuscripts for publication.
• Develop scientific proposals to apply for fellowships.
• Identify problems that may adversely affect experiments or the reporting of results, take corrective action, or notify appropriate supervisory personnel.
• Comply with Endeavor Health research guidelines.
• Follow Institutional Review Board (IRB) regulations and local, state, and federal research regulations.
• Assist with submission of research applications, revisions, and periodic progress reports.
• Participate in single-cell ATAC-seq/RNA-seq experiments and analyses.

Benefits

• Premium pay such as shift, on-call, and holiday pay, based on the employee’s job and eligibility.
• Incentive pay for select positions.
• Opportunity for annual increases based on performance.
• Career pathways to promote professional growth and development.
• Medical, dental, pet, and vision options.
• Tuition reimbursement.
• Free parking.
• Wellness program.
• Savings plan.
• Health savings account options.
• Retirement options with company match.
• Paid time off and holiday pay.
• Community involvement opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree