Post-Doctoral Fellow

University of Colorado • Aurora, CO

4d • Onsite

About The Position

The University of Colorado Anschutz Medical Campus is a world-class medical destination at the forefront of transformative science, medicine, education and patient care. The campus encompasses the University of Colorado health professional schools, more than 60 centers and institutes, and two nationally ranked independent hospitals - UCHealth University of Colorado Hospital and Children's Hospital Colorado - that treat more than two million adult and pediatric patients each year. Innovative, interconnected and highly collaborative, the University of Colorado Anschutz Medical Campus delivers life-changing treatments, patient care and professional training and conducts world-renowned research fueled by over $757 million in research grants. For more information, visit www.cuanschutz.edu. The Division of Hematology at the University of Colorado Anschutz Medical Campus has an opening for a full-time Post-Doc in the Meyer Laboratory. This position is expected to work independently under the guidance of the principal investigator. Projects will involve work with animal model and human patient sample experiments to investigate immune function in cell therapy and hematopoietic stem cell transplantation for malignant and non-malignant diseases, extensive development and use of cutting-edge flow cytometry, molecular biology, experimental therapeutics studies on novel agents, and cell biology assays on rare bone marrow-derived hematopoietic populations.

Requirements

• A doctoral level degree (PhD, MD, MD/PhD) in immunology, stem cell biology, experimental hematology, molecular biology, or equivalent from an accredited institution.
• At least one first-author publication in an internationally recognized, peer-reviewed journal.
• One year experience or PhD.
• Candidate must be able to work with laboratory animals and animal tissues.
• Candidate must meet eligibility requirements for NIH T32 and F32 postdoctoral fellowship awards.
• Excellent written and verbal communication skills.
• Ability to work independently and as a team member within a research environment.
• Ability to work efficiently and effectively with computer software including Microsoft Office.
• Skilled with the use of aseptic mammalian cell culture techniques.
• Skilled with common laboratory techniques and equipment consistent with PhD-level graduate training.
• Ability to commit to an independent scientific career in stem cell biology, immunology, or a related field, with a proven high degree of independence and self-motivation to achieve these ends.
• Ability to work a flexible schedule based on the needs of the project.

Nice To Haves

• Specific experience with leukemia research.
• Graduate training in a biomedical laboratory setting, studying immunology, molecular biology, hematology and/or stem cell biology.
• Experience with the use of advanced flow cytometry equipment (including LSRII and FACSAria II) for analysis and sorting of cells, and development of multicolor antibody staining panels.
• Experience in mouse handling, husbandry and dissection.
• Experience in experimental hematology and molecular biology assays and techniques, including HSC isolation and analysis, and high-throughput sequencing.
• Candidates that have successfully obtained competitive, extramural funding during their doctoral studies are preferred.

Responsibilities

• Responsible for conducting a pre-clinical evaluation of cell therapy approaches in murine models of transplantation tolerance and hematopoietic stem cell transplantation.
• Responsible for conducting correlative science evaluation of peripheral blood biospecimens from patients undergoing stem cell transplantation and/or cellular therapy.
• Responsible for independently plan, execute and analyze experiments under supervision and will be responsible for communicating results through abstract presentations and publications.
• Required ability to handle, breed and contribute to protocols that allow for the evaluation of mouse models.
• Execute and process flow cytometry, ELISA, histology, RNA-Seq, TCR-Seq and other immune assays.
• Process and perform experiments with human peripheral blood and contribute to biobanking of these samples.
• Contribute to the training of graduate, medical and post-doctoral candidates.
• Contributing to collaborations with the Barbara Davis Center and Gates Center pertaining to the clinical translation of advanced cell therapy approaches to the clinic.
• Other duties as assigned

Benefits

• Comprehensive benefits package
• Generous leave
• Health plans
• Retirement contributions

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree