Post-Doc Research Associate - Arthur Lab

UNC-Chapel HillChapel Hill, NC
Onsite

About The Position

The Arthur lab is seeking an enthusiastic and highly-motivated Postdoctoral Research Associate to investigate interactions between the microbiota and intestinal disease, specifically inflammation, fibrosis, and colorectal cancer. The lab utilizes germ-free and gnotobiotic mice to causally link specific microbes, microbial genes, and microbial metabolites with health and disease in the gut. Approaches include microbiology, immunology, and molecular biology, often integrated with multiomics technologies like RNAseq and spatial profiling. Available projects focus on defining microbial mechanisms driving inflammation-associated intestinal fibrosis and identifying novel regulators of colibactin production and resulting tumorigenesis. The role involves independent biomedical research, including project development, experimental design, data analysis/interpretation, and communication of results. Additional responsibilities may include managing lab resources, mentoring trainees, and contributing to grant writing. Opportunities for presenting work at conferences and publishing manuscripts are ample. The position is in a dynamic working environment ideal for developing an independent research program, located in Marsico Hall within the Dept. of Microbiology and Immunology, and affiliated with the Center for Gastrointestinal Biology and Disease (CGIBD) and Lineberger Comprehensive Cancer Center (LCCC). The primary purpose is to perform experiments, analyze and interpret data, and communicate results under minimal supervision, with potential for training graduate students, lab management, and assisting with grant writing.

Requirements

  • PhD in immunology, microbiology, or a related area of biomedical sciences
  • Experience performing in vitro and/or in vivo biological experiments
  • Strong record of research productivity
  • Interest in host:microbiome interactions relevant to digestive diseases
  • Willingness to work with commensal bacteria, intestine and stool samples
  • Willingness to work with mice and become proficient in mouse models of intestinal inflammation and cancer, including necropsy procedures

Nice To Haves

  • Demonstrated knowledge and experimental expertise in mouse models of infection, intestinal inflammation and/or cancer
  • Demonstrated knowledge and experimental expertise in molecular microbiology
  • Demonstrated knowledge and experimental expertise in tissue culture

Responsibilities

  • Perform experiments
  • Analyze and interpret data
  • Communicate results both independently and in a team setting
  • Participate in independent biomedical research, including project development, experimental design, data analysis/interpretation
  • Manage lab resources
  • Mentor graduate students and other trainees
  • Contribute to grant writing
  • Present work at conferences/symposia
  • Publish manuscripts
  • Train graduate students and other trainees
  • Help manage the lab
  • Assist the PI in grant writing
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