Post-Doc Fellow - Tse Lab

University of Kansas Medical Center • Kansas City, MO

3d • $63,480 - $90,000 • Onsite

About The Position

A postdoctoral position is available in the laboratory of Dr. Hubert Tse in the Department of Microbiology, Molecular Genetics, and Immunology at the University of Kansas Medical Center. Our research program seeks to increase our understanding of the immunological and molecular mechanisms involved in autoimmune dysregulation in Type 1 diabetes (T1D). Through the use of novel murine models of T1D, human translational studies, and innovative technologies including spatial transcriptomics, single cell RNA-sequencing, and induced-pluripotent stem cells, we are interested in determining how reactive oxygen species (ROS) synthesis contributes to innate immune responses and autoreactive T cell effector mechanisms involved in pancreatic -cell destruction. Additional research projects in the lab include the use of novel immunoprotection strategies to delay islet transplantation rejection and to define the role of insulin-producing -cells in T1D. We seek a motivated, creative, and energetic applicant with excellent communication skills and organization. The laboratory uses immunological methods, molecular biology, cellular biochemistry, redox biology, murine models, imaging, and flow cytometry to discover and evaluate new mechanisms of autoimmune dysregulation. If interested, please send a letter describing your research experience/interest/future career aspirations, your CV, and contact information for three references.

Requirements

• PhD in Microbiology, Immunology, Biochemistry, Molecular Biology, or related field.
• 4 years related research experience.
• This position requires a formal degree in the cited discipline area(s) to ensure that candidates have the foundational knowledge and skill set required to perform the duties of the position.
• Resume/CV
• Cover Letter

Responsibilities

• Conduct mentored research in induced-pluripotent stem cell-derived macrophages to examine their ability to delay autoimmune responses.
• Perform spatial transcriptomics to increase our understanding of the role of b-cells in Type 1 diabetes.
• Perform data analysis, prepare data for presentations (oral and written), write manuscripts and other research documents.
• Attend and maintain compliance on all orientation and training sessions designated by the University and the Department of Microbiology, understand and follow all assigned duties, and attend regularly scheduled research team meetings.
• Complete research projects under the guidance of the faculty mentor, record and interpret the results of their experiments in an (electronic) laboratory notebook, prepare publication-quality manuscripts (including figures and tables) and publish in peer-reviewed literature.
• Read literature articles, develop new ideas, and assimilate the information into his/her project design/interpretation.
• Interact on a regular basis with their faculty mentor and members of the laboratory to discuss experimental design and interpretation of results.
• Present research aims and findings at department seminars and at scientific meetings.
• Write and publish their results as first author in abstracts, manuscripts, and posters.
• Submit fellowship applications, as eligible, to bolster research funding and CV building for projects.

Benefits

• health insurance
• dental insurance
• vision insurance
• health expense accounts with generous employer contributions
• Employer-paid life insurance
• long-term disability insurance
• various additional voluntary insurance plans
• Paid time off, including vacation and sick
• ten paid holidays
• One paid discretionary day is available after six months of employment
• paid time off for bereavement, jury duty, military service, and parental leave is available after 12 months of employment
• A retirement program with a generous employer contribution
• additional voluntary retirement programs (457 or 403b)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree