Mass Spectrometry Chemist

General Matter•Los Angeles, CA

22h•$100,000 - $150,000•Onsite

About The Position

As a Mass Spectrometry Chemist at General Matter, you will play a critical role in establishing and advancing our analytical measurement capabilities for uranium isotopic analysis. You'll work hands-on with cutting-edge mass spectrometry instrumentation — including isotope-ratio mass spectrometry and ICP-MS systems — to develop, validate, and execute methods that directly support our enrichment operations and product certification. This is a rare opportunity to build measurement systems from the ground up at a next-generation nuclear facility during rapid commercial scale-up, where your technical work immediately impacts our ability to produce low-cost nuclear fuel at scale. If you seek high impact and are excited by fast-paced, intense, Skunkworks-style projects in service of a mission of national importance, we encourage you to apply to join our Chemistry team.

Requirements

Bachelor's degree in Chemistry, Radiochemistry or a related field, or equivalent experience
Hands-on laboratory experience with mass spectrometry techniques (ICP-MS, isotope-ratio MS, or similar)
Demonstrated ability to develop, troubleshoot, and optimize analytical methods and instrumentation
Strong problem-solving skills and attention to detail in data collection, analysis, and documentation
Evidence of exceptional ability — prior research projects, published work, or demonstrated technical contributions in analytical chemistry or instrumentation
Ability to obtain and maintain required security clearance and access authorization for work with nuclear materials
Ability to work on-site in Los Angeles, CA or Paducah, KY

Nice To Haves

Experience with uranium isotopic analysis, nuclear materials characterization, or safeguards measurement techniques
Familiarity with TIMS, MC-ICP-MS, or other isotope-ratio mass spectrometry platforms
Prior work in a DOE national laboratory, NRC-licensed facility, nuclear fuel-cycle company, or instrumentation vendor environment
Experience in method validation, regulatory compliance (e.g., DOE, NRC, ISO standards), or quality assurance in analytical chemistry
Background in fast-paced, resource-constrained, or startup environments where autonomy and bias toward action are required
Strong communication skills and ability to collaborate across technical and operational teams

Responsibilities

Develop, optimize, and validate analytical methods for uranium isotopic analysis using mass spectrometry (isotope-ratio MS, ICP-MS)
Perform isotopic sampling, sample preparation, and measurement workflows to support enrichment process monitoring and product certification
Operate, maintain, calibrate, and troubleshoot mass spectrometry instrumentation to ensure measurement accuracy, precision, and reliability
Integrate measurement systems with sample-handling workflows and support automation and process improvements
Collaborate closely with the Chemistry team and cross-functional partners (Operations, Product Certification, Engineering) to define analytical requirements and deliver results that drive decision-making
Document methods, maintain rigorous QA/QC protocols, and support regulatory and compliance reporting as needed
Contribute to continuous improvement of analytical capabilities as General Matter scales production