Senior Scientist, Mass Spectrometry
About The Position
Bristol Myers Squibb is seeking a Senior Scientist, Mass Spectrometry to join their team in New Brunswick, NJ. This role involves designing, developing, and executing methods for trace-level quantitative analysis of impurities in drug substances and products using LC/high-resolution mass spectrometry. The scientist will apply high-resolution MS and MS/MS techniques for structural characterization of impurities and degradants in small molecule drug compounds, and perform mass spectrometry-driven peptide mapping for biologic therapeutics to support pharmaceutical formulation development. Responsibilities also include instrument maintenance, user training, influencing initiatives to improve structure elucidation capabilities, active participation in team meetings, delivering high-quality data, collaborating with subject matter experts, presenting scientific data, drafting technical reports, and representing the analytical function in matrix teams. The role also encourages expanding skills in techniques beyond mass spectrometry, such as NMR, to become a more complete structure elucidation scientist.
Requirements
- PhD degree or foreign equivalent degree in Chemistry, or a related field, and one (1) year of related work experience.
- Developing and running mass spectrometry-based quantitation assays that are capable of trace level analysis.
- Analyzing impurities and/or degradants using LC-MS, with accurate mass, and MS/MS for the characterization and assignment of unknown chemical structures.
- Operation and trouble shooting of a variety of modern Thermo-Fisher Scientific mass spectrometers including data analysis with Xcalibur.
- Utilizing Python, R, and MATLAB languages for data analysis and visualization (six (6) months of experience).
Responsibilities
- Independently design, develop, and execute methods capable of trace-level, quantitative analysis of impurities in drug substance and drug product using innovative and robust LC/high-resolution mass spectrometry workflows.
- Apply high resolution MS and MS/MS techniques for the structural characterization of impurities and degradants arising in small molecule drug compounds.
- Characterization of biologic therapeutics using mass spectrometry driven peptide mapping analysis to support pharmaceutical formulation development activities.
- Involved with instrument maintenance and user training.
- Influence scientists and initiatives to improve efficiency, productivity, and evolution of our structure elucidation capabilities.
- Engage in active discussions within team meetings and deliver high quality data within timelines.
- Collaborate with other subject matter experts to continually develop project knowledge, meet project goals, and enable capabilities within the department.
- Presentation of scientific data, drafting of expert technical reports, and representation of the analytical function in matrix team meetings.
- Expansion of skills in techniques beyond the primary expertise of mass spectrometry, such as NMR, to become a more complete structure elucidation scientist.
Benefits
- Annual discretionary bonus
- Health Coverage: Medical, pharmacy, dental, and vision care.
- Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
- Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
- Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
- Unlimited paid sick time
- Up to 2 paid volunteer days per year
- Summer hours flexibility
- Leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs
- Annual Global Shutdown between Christmas and New Years Day
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
