Macromolecular Crystallographer Scientist - IMCA-CAT & AUI, Inc.

Nonprofit HR • Chicago, IL

20d • $100,000 - $114,000 • Onsite

About The Position

The Industrial Macromolecular Crystallography Association - Collaborative Access Team (IMCA‑CAT) and Associated Universities, Inc. (AUI) seek an inventive macromolecular crystallography scientist to join the IMCA‑CAT team in accelerating pharmaceutical drug discovery through synchrotron-based structural biology research. The IMCA consortium, which funds and provides strategic guidance to IMCA-CAT, consists of AbbVie, Bristol Myers Squibb, Evotec, Johnson&Johnson, Merck, Novartis, Pfizer, and Relay Therapeutics. As an employee of AUI, you will be based at the center of the team’s operations at the Advanced Photon Source (APS), Argonne National Laboratory, near Chicago, IL. This is an ideal position for a motivated scientist who is passionate about delivering strategic value, developing new technologies, and working in a high-powered, collaborative environment. This is an exciting time to join IMCA‑CAT. The team is commissioning the recently upgraded beamline that will profoundly increase capacity and dramatically expand capability for challenging research projects. As a member of the IMCA-CAT team, you will be an integral part of these commissioning activities, participate in maintaining the flow of diffraction data for pharmaceutical research projects, and contribute to innovative developments that expand the experiment envelope. You will work closely with IMCA‑CAT colleagues in an inclusive and respectful environment, and will be expected to take initiative and contribute to the team effort.

Requirements

• BS/BA in a science-related industry plus 5+ years of experience working in the pharmaceutical industry, specializing in macromolecular crystallography.
• Outstanding experimental skills and strong technical skills.
• Highly collaborative and team-oriented approach to conducting work and solving problems.
• Excellent written and oral communication skills.
• Deeply proactive approach to meeting and exceeding goals.
• Ability to routinely lift racks of samples (5 lbs), baskets of samples in liquid nitrogen (15 lbs), and shipping dewars (up to 35 lbs).
• Ability to meet requirements for site access to Argonne National Laboratory.

Responsibilities

• Ensure the beamline produces data of the highest quality.
• Conduct high-resolution, single-crystal protein X-ray diffraction experiments in support of drug discovery research efforts at both IMCA-CAT and a variety of external synchrotron sources.
• Lead the effort in managing incoming and outgoing samples.
• Manage test crystals for quality control performance of the beamline.
• Contribute to the weekly maintenance of beamline equipment, including robot and staging dewars.
• Develop and expand the structural biology services that support pharmaceutical structure-based drug design.
• Contribute to the development and implementation of technologies that expand the experiment envelope.
• Establish efficient protocols for accelerating data acquisition while enhancing data security.
• Collaboratively develop automated methods for acquiring quality data from challenging samples.
• Engage in the technical development of new strategies for ultra-high throughput.
• Collaborate with the team on strategically aligned research and development projects.
• Communicate with researchers and present at meetings.
• Manage and maintain the biochemistry laboratory space.

Benefits

• AUI offers a full and competitive benefits package.
• The compensation level for this full-time position will be competitive and commensurate with the candidate’s qualifications.
• AUI provides a generous benefits package.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior