Laboratory Research Technician III
About The Position
Eagle Integrated Services, LLC (EIS) is seeking a Laboratory Research Technician to support cell culture and animal research at the U.S. Army Medical Research Institute of Chemical Defense (USAMRICD). The technician will maintain cell cultures; support physiological, pharmacological, and behavioral studies; document and analyze research data; and collaborate with the principal investigator (PI) and research team in applied medical defense research. The role includes maintaining stem cell, microglia, and organoid cultures; preparing media, solutions, and reagents; conducting assays and microscopy-related procedures; and maintaining cell banks, inventories, and laboratory equipment. Animal research duties include monitoring and handling nonhuman primates and small animals, supporting experimental and surgical procedures, administering compounds as authorized by approved protocols, and collecting physiological, behavioral, blood, and tissue data. The technician will keep laboratory records, analyze and compile data, contribute to research reports and other written products, assist with protocols and experimental design, and work in accordance with applicable safety, security, surety, IACUC, and standard operating procedure requirements. The position requires U.S. citizenship and an active DoD Interim SECRET security clearance.
Requirements
- Degree in biological sciences, such as biology, neuroscience, or cell and molecular biology, or in psychology.
- Knowledge of pharmacology, neuroscience, and applied medical defense research.
- Experience scheduling and executing cell culture protocols and maintaining microglia, stem cells, or organoid cultures.
- Experience executing animal use protocols and handling nonhuman primates (NHPs).
- Experience handling small animals, with rats preferred, or at least one year of animal or husbandry research experience.
- Experience with fluorescence or two-photon microscopy hardware and software.
- Experience with Microsoft Excel and Word.
- Experience with GraphPad Prism or similar statistical software.
- Experience with DSI hardware and software.
- Excellent written and oral communication skills and adaptability to new research teams or project assignments.
- U.S. citizenship.
- An active DoD Interim SECRET security clearance.
Nice To Haves
- Background in organotypic or acute brain slice culture.
- Experience with in vitro electrophysiology techniques, such as microelectrode arrays and whole-cell patch clamp.
- Proficiency with EthoVision XT software.
- Experience handling rats.
Responsibilities
- Monitor, culture, passage, and maintain stem cells, microglia, and organoids using appropriate cell culture and molecular biology techniques, and monitor cultures for contamination or changes that may affect results.
- Prepare and replenish media, solutions, and reagents; perform dilutions; and maintain multiple cell and organoid culture lines concurrently.
- Maintain cell line banks, stock solutions, media, chemical inventories, and laboratory equipment; perform routine assays and follow equipment manufacturer guidance.
- Perform immunohistochemical staining, cryostat sectioning, and microscopy, and develop or modify analytical methods using computer-assisted microscopy and histological procedures.
- Monitor nonhuman primates and small animals during the workday and support physiological, pharmacological, and behavioral studies.
- Handle and restrain animals; assess health and behavior; track weight; and administer pharmaceutical or chemical compounds as authorized by approved protocols.
- Assist with pre-surgical, surgical, and post-surgical procedures, including implantation of telemetry or related physiological monitoring devices; habituate animals to behavioral equipment and restraint devices.
- Schedule and conduct experimental procedures, including test drug preparation, solubility studies, blood sampling, physiological monitoring, behavioral testing, perfusion, and tissue dissection.
- Assess and document animal health and behavior after administration of candidate therapeutic compounds by applicable intramuscular, subcutaneous, or intravenous routes.
- Maintain accurate laboratory notebooks, daily reports, and digital and physical research records using good documentation practices, recording findings during or immediately following experiments.
- Analyze and compile data and contribute to project milestones, reports, figures, presentations, manuscripts, proposals, and other written products as requested by the PI or COR.
- Assist with research protocols, amendments, and experimental design, and communicate protocol requirements to team members, collaborators, and support personnel.
- Conduct research in accordance with applicable safety, surety, security, IACUC, and standard operating procedure requirements.
- Maintain clean and safe laboratory and animal spaces and properly dispose of potentially hazardous waste.
- Coordinate laboratory supplies, animals, and equipment to support project schedules and ensure the quality of procedures and data.
Benefits
- Paid holidays
- Paid time off, including sick and vacation leave
- Medical insurance
- Dental insurance
- Vision insurance
- Flexible spending accounts
- Short- and long-term disability
- Company-paid life insurance
- 401(k) with company match
- Discretionary profit sharing
- Tuition reimbursement
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
