IT Director

Spyglass Pharma • Irvine, CA

5d

About The Position

The Director of IT will be SpyGlass Pharma’s first dedicated in-house IT leader, responsible for IT strategy, systems administration, and infrastructure across the company’s Microsoft 365-based environment. This is initially a hands-on individual-contributor role that directs the managed IT and security services provider (MSP/MSSP) and partners with the fractional CISO. The CISO owns cybersecurity strategy, AI governance, and third-party security risk; the Director of IT operationalizes relevant policies and runs the systems that implement them.

The role will establish and manage scalable IT operations as SpyGlass Pharma grows from approximately 90 employees to 300–500, including support for additional office locations. The Director will collaborate with business functions, oversee vendors and enterprise platforms, ensure applicable regulatory alignment, and build the case for hiring the company’s first internal IT support or systems team member within the first year.

Requirements

• Bachelor’s degree in Information Technology, Computer Science, Engineering, or a related discipline preferred; equivalent professional experience, military technical training, and industry certifications may be considered in lieu of a degree.
• At least 8–10 years of progressive IT systems experience, including hands-on individual-contributor work and leadership experience.
• Prior IT experience in a life sciences, pharmaceutical, biotech, or other GxP-regulated company, with working knowledge of 21 CFR Part 11, GAMP 5, and computer system validation.
• Deep, hands-on experience administering Microsoft 365, Entra ID, Intune, and Conditional Access.
• Experience managing an outsourced MSP or IT vendor relationship, including SLA management and vendor governance.
• Ability to operate as the sole IT leader initially, working hands-on and strategically, and build the case for and onboard the first internal IT hire within the first year.
• Strong interpersonal skills and ability to lead cross-functional initiatives and communicate effectively across all levels of the organization.

Nice To Haves

• Experience supporting SOX IT General Controls (ITGCs), including access reviews, change management, and segregation-of-duties controls.
• Experience scaling an IT function through a significant headcount inflection point, such as helping a company grow from roughly 100 to 400 or more employees.
• Exposure to clinical, quality, or ERP systems such as Veeva, MasterControl, NetSuite, or similar platforms.

Responsibilities

• Lead the design, implementation, and administration of IT infrastructure, including Microsoft 365, Entra ID, Intune, networking, and cloud environments.
• Own the configuration, security, maintenance, monitoring, and upgrades of enterprise IT systems, including Egnyte, NetSuite, MasterControl, Bamboo, Veeva Vault, and iMednet/Medrio.
• Direct and manage the outsourced IT and help desk provider, including service-level agreements, escalations, and evaluating which services should remain outsourced as the company scales.
• Partner with the fractional CISO to operationalize cybersecurity, AI governance, and access-control policies.
• Develop and implement scalable IT policies, standard operating procedures, and governance frameworks, including support for new office locations.
• Oversee system backup and disaster recovery planning, execution, and testing.
• Collaborate with Quality, Clinical, Commercial, Finance, HR, and other business functions to assess IT needs, implement solutions, and support strategic projects.
• Manage user access, system provisioning, and secure integrations across business platforms; build scalable onboarding, offboarding, and device-lifecycle processes.
• Advise on IT project management and cross-functional support, ensuring documentation, timeline management, and issue resolution.
• Lead vendor evaluations and manage third-party hardware, software, and IT service partnerships; evaluate and implement tools and platforms as the company grows.
• Develop the business case for and hire the first internal IT support or systems team member within the first year, then mentor and guide the team as it grows.
• Ensure IT systems operations align with 21 CFR Part 11, other relevant GxP requirements, and SOX IT general controls where applicable.
• Provide end-user support and training with a service-oriented approach.

Benefits

• Annual bonus opportunity.
• Stock options.
• Health insurance with a variety of plan and coverage options.
• Dental insurance with a variety of plan and coverage options.
• Vision insurance with a variety of plan and coverage options.
• Paid time off, including holidays, vacation days, and personal leave.

What This Job Offers

• Job Type: Full-time
• Career Level: Director