2027 Future Talent Program – Protein and Structural Chemistry – Co-op
About The Position
The Future Talent Program offers cooperative education placements lasting 4–6 months and involving one or more projects. This six-month Co-op is with the Boston Structural Chemistry group in the Protein and Structural Chemistry department within Discovery Chemistry. The group uses X-ray crystallography, cryo-electron microscopy (cryo-EM), and complementary structural biology approaches to determine high-resolution structures of therapeutically relevant targets and drug-target complexes, supporting structure-based drug discovery across research programs. The Co-op will gain hands-on experience with modern structural biology workflows and contribute to projects from early discovery through late-stage development. Depending on project needs and the candidate’s experience, the work may include protein crystallization screening, cryo-EM sample preparation, diffraction or imaging data collection, data processing, structure determination, model building, and structural analysis. The Co-op will work with structural biologists and collaborate with protein scientists, medicinal chemists, computational chemists, and biophysicists to generate insights that guide drug design. The Co-op will participate in departmental and project team meetings and communicate scientific results through presentations, written reports, and internal research symposia. Other duties include maintaining accurate electronic laboratory records, operating structural biology laboratory instrumentation, and following safety and compliance requirements. The position requires full-time availability for six consecutive months beginning in 2027 and on-site laboratory work in the Boston area.
Requirements
- Currently enrolled in a graduate degree program in Structural Biology, Biochemistry, Biophysics, Molecular Biology, Chemistry, or a related discipline.
- Available to work full-time for six consecutive months beginning in 2027.
- Willing to relocate to the Boston area for on-site laboratory work.
- Strong organizational, analytical, and communication skills.
- Ability to work effectively in a highly collaborative, team-oriented environment.
- Experience with one or more of the following: X-ray crystallography, cryo-electron microscopy (cryo-EM), protein biochemistry, protein crystallization, structural data processing and analysis, or molecular visualization and structure refinement software such as PyMOL, Coot, ChimeraX, or Phenix.
Responsibilities
- Contribute to structural biology projects spanning early discovery through late-stage development.
- Depending on project needs and candidate experience, perform protein crystallization screening and cryo-EM sample preparation.
- Collect diffraction or imaging data and perform data processing, structure determination, model building, and structural analysis as applicable.
- Collaborate with structural biologists, protein scientists, medicinal chemists, computational chemists, and biophysicists to generate insights that guide drug design.
- Participate in departmental and project team meetings.
- Communicate scientific results through presentations, written reports, and internal research symposia.
- Maintain accurate electronic laboratory records.
- Operate laboratory instrumentation used in structural biology research.
- Follow safety and compliance requirements.
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What This Job Offers
Job Type
Full-time
Career Level
Intern
