Executive Director, Global Medical Oncology, Iza-Bren Medical Product Lead (MPL)

Bristol Myers Squibb • Princeton, NJ

5d

About The Position

Bristol Myers Squibb seeks an innovative, results-oriented leader to serve as the Iza-Bren Medical Product Lead (MPL) in Global Medical Oncology. The role leads the Global Medical team for Izabren (BMS-986507), a first-in-class EGFRxHER3 bispecific antibody-drug conjugate co-developed with SystImmune, with a multi-tumor development program spanning breast, lung, gastrointestinal, and genitourinary cancers. The MPL leads a mission-focused team to accelerate clinical evidence generation, recruitment, education, and external advocacy across international markets as the program advances toward registration and launch. The role drives unified strategy, execution, and end-to-end ownership across Global Oncology, and reports to the VP, Worldwide Medical Affairs Disease Area Head, Thoracic & H&N Cancers.

In collaboration with SystImmune, the MPL develops and executes global medical strategy across tumor types and lines of therapy, leads dedicated Global and US medical teams, and ensures alignment of messaging, evidence, and education. The role is accountable for execution across international, regional, and field levels; trial execution and site engagement; competitive monitoring; budget and resource allocation; KPI and dashboard oversight; and collaboration with development, safety, biomarker, regulatory, alliance, and international teams.

The MPL supports a high-performing team of regional leads and dedicated MSLs, advances scientific advocacy and medical education, engages key opinion leaders and investigators, and plans data dissemination at congresses. The role also partners across Medical, Development, Commercial, Market Access, and Patient Advocacy to support pre-launch readiness and portfolio value, and represents Izabren in stakeholder, partnership, and joint governance meetings.

Requirements

• Advanced degree in medicine, science, or a related field (MD, PhD, or PharmD); MD preferred.
• 15+ years of medical affairs, development, or commercial experience, with a strong track record in international markets.
• Pharmaceutical experience in solid tumors is required, including breast, thoracic, gastrointestinal, and genitourinary cancers.
• Proven expertise leading large, geographically distributed teams and driving high performance in competitive environments.
• Deep understanding of regulatory, healthcare, and cultural diversity across international markets.
• Demonstrated ability to execute strategies that deliver measurable business and patient outcomes.
• Strong cross-functional leadership and stakeholder management skills.
• Ability to collaborate effectively across boundaries such as R&D, disease management, marketing, and external development, and build strong external relationships.
• Strong project management capabilities and experience in change management, leading teams through market or organizational transformation.
• Ability to represent the global team and communicate effectively, influencing decisions with senior leadership and matrix teams.

Nice To Haves

• Experience with ADCs, bispecific antibodies, and/or Phase 3 oncology development is strongly preferred.

Responsibilities

• Develop and execute a unified global medical strategy for Izabren across tumor types and lines of therapy, aligned with global and US strategy.
• Lead and manage dedicated Global and US medical Izabren teams, aligning messaging, evidence, and education.
• Drive rapid decision-making and execution, removing delays associated with traditional matrix models.
• Ensure direct accountability at international, regional, and field levels, with real-time progress tracking and intervention.
• Optimize trial execution and site engagement across diverse markets for the global Izabren program, including Phase 2/3 and Phase 3 studies in breast, lung, and urothelial cancer.
• Monitor the competitive landscape and adapt strategies to maintain leadership.
• Oversee resource allocation, budget management, and strategic prioritization.
• Establish and monitor KPIs, dashboards, and reporting tools for continuous improvement.
• Partner with Clinical Development, Safety, Translational/Biomarker, and Regulatory teams so medical insights and real-world evidence needs inform the development plan and future label.
• Collaborate with the Alliance Lead and SystImmune counterparts to maintain joint medical and scientific alignment across territories.
• Support and empower regional Izabren leads and dedicated MSLs to accelerate site activation, recruitment, medical education, and scientific advocacy.
• Engage key opinion leaders, investigators, and professional societies, and plan data dissemination at key congresses.
• Partner with Global Medical, Development, Commercial, Market Access, and Patient Advocacy teams to support pre-launch excellence and portfolio value.
• Represent Izabren in stakeholder and partnership meetings, including joint governance with SystImmune, and drive cross-functional alignment.

Benefits

• Comprehensive benefit plans, including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance.
• Flexible Time Off for eligible U.S.-based exempt employees, subject to manager approval.
• Paid company holidays.
• Additional eligible time-off benefits may include paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees may receive an annual Global Shutdown between Christmas Day and New Year's Day.
• May be eligible for discretionary incentive cash and stock opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Director