Executive Director, Global Medical Oncology, Iza-Bren Medical Product Lead (MPL)

Bristol Myers Squibb • Princeton, NJ

6d • $254,530 - $308,434

About The Position

Bristol Myers Squibb seeks an innovative, results-oriented leader to serve as the Iza-Bren Medical Product Lead for Global Medical Oncology. The role leads the Global Medical team for Izabren (BMS-986507), a first-in-class EGFRxHER3 bispecific antibody-drug conjugate co-developed with SystImmune. The program spans breast, lung, gastrointestinal, and genitourinary cancers. The Medical Product Lead will direct a mission-focused team to accelerate clinical evidence generation, recruitment, education, and external advocacy across international markets. The position will drive unified strategy, high-velocity execution, and end-to-end ownership across Global Oncology as the program advances toward registration and launch.

In collaboration with SystImmune, the role leads global medical strategy across tumor types and lines of therapy, and manages dedicated global and U.S. medical teams. It is accountable for execution and progress across international, regional, and field levels; trial execution and site engagement; competitive monitoring; resource and budget oversight; and performance measurement. The role works with clinical development, safety, translational and biomarker, regulatory, alliance, and international teams to ensure medical insights and real-world evidence needs inform development plans and future labeling.

The position also builds and empowers regional leads and dedicated medical science liaisons, strengthens scientific advocacy and medical education, and engages key opinion leaders, investigators, and professional societies. It partners with Global Medical, Development, Commercial, Market Access, and Patient Advocacy teams to support pre-launch excellence and portfolio value, and represents Izabren in stakeholder, partnership, and joint-governance meetings. The role reports to the VP, Worldwide Medical Affairs Disease Area Head, Thoracic & H&N Cancers.

Requirements

• Advanced degree in medicine, science, or a related field (MD, PhD, or PharmD); MD preferred.
• At least 15 years of medical affairs, development, or commercial experience, with a strong track record in international markets.
• Pharmaceutical experience in solid tumors is required, including breast, thoracic, gastrointestinal, and genitourinary cancers.
• Proven expertise leading large, geographically distributed teams and driving high performance in competitive environments.
• Deep understanding of regulatory, healthcare, and cultural diversity across international markets.
• Demonstrated ability to execute strategies that deliver measurable business and patient outcomes.
• Strong cross-functional leadership and stakeholder management skills, including the ability to collaborate across R&D, disease management, marketing, and external development and build external relationships.
• Outstanding project management capabilities and experience in change management, including leading teams through market or organizational transformation.
• Ability to provide a strong voice to the global team and communicate with and influence senior leadership and matrix teams.

Nice To Haves

• Experience with ADCs, bispecific antibodies, and/or Phase 3 oncology development is strongly preferred.

Responsibilities

• Develop and execute a unified global medical strategy for Izabren across tumor types and lines of therapy, aligned with global and U.S. strategy.
• Lead and manage dedicated global and U.S. Izabren medical teams, aligning messaging, evidence, and education across the enterprise.
• Drive rapid decision-making and execution, removing delays associated with traditional matrix models.
• Ensure accountability and real-time progress tracking at international, regional, and field levels, intervening as needed.
• Optimize trial execution and site engagement across markets for the global Izabren program, including Phase 2/3 and Phase 3 studies in breast, lung, and urothelial cancer.
• Monitor the competitive landscape, including EGFR-, HER3-, and TROP2-directed ADCs, bispecifics, and standard-of-care chemotherapy, and adapt strategies as needed.
• Oversee resource allocation, budget management, and strategic prioritization.
• Establish and monitor KPIs, dashboards, and reporting tools to support continuous improvement.
• Partner with Clinical Development, Safety, Translational/Biomarker, and Regulatory teams so medical insights and real-world evidence needs inform the development plan and future label.
• Collaborate with the Alliance Lead and SystImmune counterparts to align medical and scientific work across territories.
• Build and empower regional Izabren leads and dedicated MSLs to support scientific advocacy, site activation, recruitment, and medical education, including ADC toxicity management, dose optimization, and biomarker strategy.
• Engage key opinion leaders, investigators, and professional societies; shape external perception and scientific leadership; and plan data dissemination at key congresses.
• Partner with Global Medical, Development, Commercial, Market Access, and Patient Advocacy teams to support pre-launch excellence and maximize portfolio value.
• Represent Izabren in stakeholder and partnership meetings, including joint governance with SystImmune, and drive cross-functional alignment and enterprise initiatives.

Benefits

• Comprehensive benefit plans, including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance.
• U.S.-based exempt employees are eligible for Flexible Time Off without a set accrual limit, subject to manager approval.
• 11 paid company holidays each year.
• Depending on eligibility, additional time-off benefits may include paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees receive an annual Global Shutdown between Christmas Day and New Year's Day.
• Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires, subject to manager approval, and three optional holidays.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive