Director, Real-World Evidence & Health Outcomes, mRNA Vaccines

GSK • Philadelphia, PA

4d • $203,775 - $339,625

About The Position

The Director, Real-World Evidence & Health Outcomes (RWE-HO), mRNA Vaccines provides scientific and strategic leadership for developing and delivering real-world evidence to support GSK's mRNA vaccine portfolio, primarily influenza. The role shapes evidence generation across late-stage development, launch and post-marketing phases, with particular responsibility for post-marketing vaccine effectiveness studies in the United States. In a global, cross-functional environment, the Director translates recommendation and access evidence needs into scientifically rigorous and operationally feasible research.

The role calls for deep expertise in US vaccine effectiveness research, influenza epidemiology, real-world data and causal methods, as well as the ability to influence asset strategy and lead complex external collaborations. The Director contributes to integrated evidence strategy across the product lifecycle, supports governance and investment decisions, leads external research partnerships, and builds RWE-HO capabilities and standards across the organization.

Requirements

• PhD, ScD, DrPH, MD, PharmD, MPH or equivalent advanced degree in epidemiology, public health, pharmacoepidemiology, health outcomes research or a related quantitative discipline.
• At least 5 years of experience in real-world evidence, epidemiology or health outcomes research within the pharmaceutical or vaccine industry, academia, public health or a comparable environment.
• Experience designing, conducting and interpreting post-marketing vaccine studies in the United States.
• Research experience with vaccine effectiveness studies.
• Experience using large US healthcare databases, including administrative claims, electronic health records or linked real-world datasets.
• Experience leading complex studies from concept through delivery, interpretation and scientific dissemination.
• Demonstrated effectiveness in global, cross-functional matrix teams and in managing internal and external stakeholders.

Nice To Haves

• Direct experience with influenza vaccine effectiveness studies in the United States.
• Experience with US Medicare, commercial claims, EHR and linked claims/EHR data.
• Knowledge of US influenza vaccination recommendations, vaccine delivery and healthcare systems.
• Experience studying severe influenza, hospitalization, cardiovascular complications or other downstream outcomes.
• Experience leading global evidence-generation plans or multi-country observational studies.

Responsibilities

• Lead and contribute to the integrated RWE-HO strategy for mRNA influenza vaccines, aligned with clinical development, medical, regulatory and commercialization priorities.
• Translate strategic evidence gaps into clear research questions and fit-for-purpose study designs across pre-launch, launch and post-marketing phases.
• Provide expert scientific input to governance decisions, investment choices, evidence prioritization and risk mitigation.
• Lead the design, implementation and interpretation of post-marketing influenza vaccine effectiveness studies in the United States and other geographies.
• Ensure studies meet appropriate standards of scientific rigor, transparency, reproducibility and fitness for their intended decision-making purpose.
• Build productive collaborations with US academic investigators, healthcare systems, data partners and vaccine effectiveness research networks.
• Partner with Clinical Development, Epidemiology, Medical Affairs, Regulatory, Safety, Biostatistics, Market Access, Data Science and Commercial teams.
• Lead multiple complex projects, budgets and external research collaborations, ensuring quality, timely delivery and appropriate escalation of risks.
• Influence senior stakeholders without direct authority and communicate complex epidemiological concepts in a clear, decision-focused manner.
• Mentor colleagues and contribute to strengthening RWE-HO capabilities, standards and innovation across the organization.

Benefits

• Annual bonus
• Eligibility to participate in a share-based long-term incentive program, dependent on role level
• Health care and other insurance benefits for employee and family
• Retirement benefits
• Paid holidays
• Vacation
• Paid caregiver/parental and medical leave

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Education Level: Ph.D. or professional degree