Director, Project Management Oncology

Jazz Pharmaceuticals • US - Home-Based - PA, PA

1d • $192,000 - $288,000 • Remote

About The Position

The Director, Project Manager is a senior strategic operational leader within Pipeline and Project Management, accountable for cross-functional leadership, operational strategy, and integrated execution across one or more oncology development programs. Acting as the operational partner to the Project Lead or Global Project Lead, the Director leads cross-functional Core Teams through the full drug-development lifecycle, driving alignment and accountability without direct authority to help accelerate medicines to patients.

The role translates strategic intent and target product profiles into executable integrated development plans, maintains reliable program information across enterprise systems, and owns active risk management and scenario planning. It optimizes timelines, resources, and operational decisions throughout development, including late-stage programs, regulatory submissions, and launch. The Director also oversees program budgets and resource needs with Finance and Resource Management, and communicates operational plans, risks, and recommendations to senior leaders and governance committees.

Requirements

• Extensive experience in the biopharmaceutical or biotechnology industry, with dedicated cross-functional R&D project management leadership.
• Demonstrated track record leading projects across the full drug-development lifecycle, from early development through clinical phases, regulatory submission, approval, and commercialization.
• Demonstrated success managing late-stage development programs.
• Strong communication and storytelling skills, including the ability to synthesize complex timeline, risk, and resource data into concise executive summaries.
• Demonstrated ability to lead without formal line authority, foster accountability, build high-performing teams, navigate ambiguity, and drive consensus among senior cross-functional leaders.
• Advanced, hands-on proficiency in Planisware and Smartsheet for enterprise scheduling, risk register maintenance, and resource demand modeling.
• Bachelor’s degree in Life Sciences, Engineering, Business, or a related field.

Nice To Haves

• Prior project management experience within Oncology, such as targeted therapies, immuno-oncology, or biologics.
• Direct experience preparing or executing major Health Authority filings, including NDA, BLA, MAA, or supplemental filings.
• Advanced degree such as a PhD, PharmD, MS, or MBA.
• PMP, PgMP, or equivalent project management certification.
• Hands-on proficiency in Oracle for enterprise scheduling, risk tracking, budget, and resource demand management.

Responsibilities

• Partner with the Project Lead to translate strategic intent and target product profiles into executable integrated development plans for oncology programs.
• Prepare executive presentations for governance and executive leaders.
• Foster a high-performing, purpose-driven team culture based on psychological safety, transparency, mutual accountability, and collaborative problem-solving.
• Lead and influence cross-functional Core Teams without direct line authority to deliver program milestones.
• Challenge operational assumptions, resolve bottlenecks, and optimize timelines and cycle times through late-stage development, regulatory submissions, and launch.
• Maintain baseline data integrity across enterprise systems, providing a transparent single source of truth for timelines, risks, budgets, and FTE resources.
• Own and drive program risk registers; conduct qualitative and quantitative risk analyses and implement mitigation and contingency plans.
• Develop operational scenarios and analyze trade-offs across speed, cost, risk, and value, providing decision-ready recommendations to governance bodies.
• Partner with Finance and Resource Management to forecast, track, and optimize program budgets, external contract spend, and cross-functional capacity requirements.
• Summarize timelines, resource requirements, and critical program risks in concise communications and decision memos for senior leadership and governance committees.

Benefits

• Medical insurance
• Dental insurance
• Vision insurance
• 401(k) retirement savings plan
• Flexible paid vacation
• May be eligible for discretionary annual cash bonus or incentive compensation, depending on role
• May be eligible for discretionary equity grants

What This Job Offers

• Job Type: Full-time
• Career Level: Director