Director, Clinical Sciences

Tango Therapeutics • Boston, MA

6d

About The Position

Tango Therapeutics is seeking a Director, Clinical Sciences for a hands-on role that provides scientific contributions to one or more clinical development programs. The Director will engage in the design, execution, analysis, and interpretation of clinical studies, ensure scientific rigor throughout study conduct, lead data review and analysis, and partner cross-functionally to advance clinical development programs. The position reports to the Executive Director, Clinical Sciences.

Requirements

• MD, PhD, PharmD, or MS in a relevant scientific discipline.
• At least 10 years of experience in clinical science or research.
• At least 5 years of experience in oncology.
• Demonstrated experience designing and managing clinical trials, including knowledge of regulatory guidelines and GCP.
• Strong analytical skills, with proficiency in statistical analysis and interpretation of clinical data.
• Excellent written and oral communication skills, including the ability to convey complex scientific concepts to diverse audiences.
• Experience working in a fast-paced environment.

Responsibilities

• Contribute scientifically to one or more clinical programs to support the successful design, execution, and interpretation of clinical studies.
• Provide scientific leadership throughout the design, execution, analysis, and interpretation of early- and late-stage oncology clinical trials.
• Partner with Clinical Development physicians, Clinical Operations, Biostatistics, Clinical Pharmacology, Pharmacovigilance, Regulatory Affairs, Translational Medicine, and Medical Writing to support high-quality clinical program execution.
• Contribute to the development and review of protocols, investigator brochures, informed consent forms, clinical study reports, clinical development plans, and regulatory briefing materials.
• Interpret emerging clinical, safety, PK/PD, and biomarker data to inform study conduct, dose selection, expansion opportunities, and development strategy.
• Contribute scientific expertise to regulatory submissions and health authority interactions.
• Foster a collaborative, accountable, and scientifically rigorous culture within the Clinical Science function.
• Perform additional duties and responsibilities as required.

What This Job Offers

• Job Type: Full-time
• Career Level: Director