Clinical Project Manager/Clinic Manager

Buck Institute•Novato, CA

8d•$90,000 - $100,000•Onsite

About The Position

The Buck Institute’s Clinical Research Core is seeking an organized, motivated clinical research leader to lead in-person visits for THRIVE and manage the operations of its on-site clinic. THRIVE is the clinical validation arm of PROSPR, an ARPA-H-funded program developing the first FDA registration trial for a gerotherapeutic. THRIVE develops aging-relevant outcome measures, evaluates them with participants, and tests them in a YMCA-guided lifestyle intervention. The role is split approximately evenly between THRIVE study leadership and management of a clinic running 6–10 diverse on-site studies. The position leads day-to-day study execution, participant flow, staffing, compliance, data quality, and stakeholder coordination, while also overseeing clinic visits, staff, procedures, safety reporting, training, equipment, supplies, biospecimens, clinical space, and vendors. The role supports study intake, budgets, participant payments, visit work, sample processing, data entry, and ongoing clinic improvements. The position is full-time, 40 hours per week, and onsite. The manager must be available in person or on call during clinic visit hours of 7:30 a.m. to 2:00 p.m. Salary is $90,000–$100,000 per year, commensurate with experience. Applicants must be authorized to work for any U.S. employer; visa sponsorship is not available. The Buck Institute is an independent nonprofit research institute in Marin County, California, focused on understanding and slowing aging and age-related diseases.

Requirements

One of the following levels of education and experience in clinical research or project management in a biomedical or clinical research setting: high school diploma or technical degree and 8+ years of experience; bachelor’s degree and 4+ years; or master’s or PhD degree and 2+ years.
Clinical skills or background sufficient to train, mentor, and oversee the quality of study staff performing clinical procedures.
Supervisory or team leadership experience.
Experience preparing or submitting IRB protocols, amendments, or continuing reviews.
Strong organization across concurrent studies and priorities, with reliable follow-through, initiative, and proactive problem-solving.
Excellent written, verbal, and interpersonal communication skills; ability to work independently, as part of a team, and with all levels of management.
Attention to deadlines and budgetary guidelines.
Authorization to work for any employer in the United States; employment visa sponsorship or takeover of sponsorship is not available.

Nice To Haves

Professional certification such as PMP, ACRP-CP, SOCRA CCRP, or equivalent.
Experience with project management software such as Wrike or MS Project and EDC systems such as REDCap.
Phlebotomy certification or experience.
Clinical research experience in a nonprofit or academic setting.

Responsibilities

Lead day-to-day THRIVE execution in accordance with the protocol, GCP, ICH guidelines, and Buck Clinical Research SOPs.
Translate the THRIVE protocol into participant flow and scheduling across clinic and community sites, adapting to operational changes involving staff, rooms, and equipment.
Lead two senior and two junior research associates collecting data at community locations 2–3 days per week.
Partner with the Recruitment Specialist to maintain enrollment pace, track milestones, and flag risks to study leadership.
Manage IRB compliance, including continuing reviews, amendments, and documentation; oversee data quality and query resolution, biospecimen tracking, and protection of participant PHI and sponsor confidential information.
Run THRIVE team meetings, implement protocol amendments, manage consortium partner, collaborator, and vendor relationships, and keep stakeholders informed.
Coordinate clinic visits, staff coverage, and emerging issues across studies, resolving bottlenecks, coverage gaps, role confusion, and conflicts before they affect participants or data.
Oversee procedure quality by observing procedures and reviewing source documentation.
Oversee safety reporting and escalation for adverse events, serious adverse events, adverse events of special interest, and protocol deviations, including corrective and preventive actions.
Lead, mentor, and train Clinical Research Associates; balance workloads, provide feedback, and maintain the SOP library and training records.
Serve as the first point of contact for staff, collaborators, and participants, coordinating with study medical staff, study leaders, and project managers.
Manage clinical equipment, supplies, biospecimen inventory and LIMS, clinical space, and vendors for laboratory analysis and other services.
Support new-study intake through operational reviews and budget inputs, and coordinate participant payments with finance.
Assist with study visits, sample processing, and data entry as needed; improve clinic practices and promote cultural respect and multilingual recruitment.