Clinical Genomics Advanced Practice Provider

Flatiron Health•New York, NY

About The Position

Flatiron Health is seeking an advanced practice provider to help improve and extend lives by learning from the experience of every person with cancer. As an Advanced Practice Provider on the Clinical Oncology Team, you will apply expertise in oncology and genomics to inform the design, development, and optimization of Flatiron Health’s point-of-care products, tools, and services. The Clinical Oncology Genomics APP will support the integration of genomic data, insights, and testing decision support at the point of care. This role serves as a subject matter expert at the intersection of clinical practice and precision medicine, applying experience with clinical oncology, genomic testing, test-result interpretation, and related patient care and clinical decisions. The position may be hybrid for NYC-based employees, with work from home and three office days set by the employee and team. Remote employees may choose their work location while aligning working hours with their team.

Requirements

  • Be an Advanced Practice Provider (Nurse Practitioner or Physician Assistant).
  • Have at least 5 years of oncology experience in a community or academic setting.
  • Demonstrate expertise interpreting genomic test results, such as NGS panels across vendors including Caris, FMI, and Guardant, and understand how results inform treatment decisions.
  • Have taken clinical action on genomic test results for patients.
  • Have a deep understanding of the clinical-genomics landscape, including familiarity with NCCN Guidelines, molecular diagnostics, and precision medicine workflows.
  • Communicate complex genomic concepts clearly to product managers, engineers, designers, and other non-clinical stakeholders.
  • Have experience developing or delivering training on clinical-genomics topics.
  • Be collaborative, resourceful, and able to thrive in a fast-paced environment focused on improving cancer care through technology.

Nice To Haves

  • Experience with OncoEMR or similar oncology EHRs.
  • Experience with Flatiron Assist.
  • Prior involvement in clinical research or quality improvement initiatives related to precision medicine.
  • City of Hope Genomics Risk Assessment Certification.

Responsibilities

  • Serve as a subject matter expert in clinical oncology and genomics for Flatiron’s product development teams.
  • Interpret complex genomic test results and translate clinical workflows into actionable product requirements.
  • Advise on integrating molecular diagnostics and precision medicine into Flatiron software solutions, ensuring products reflect real-world clinical needs and best practices.
  • Review and validate product features related to genomic data capture, interpretation, and clinical decision support.
  • Collaborate with Product, Engineering, and Clinical teams to inform and test enhancements to clinical workflows in OncoEMR and other Flatiron products.
  • Represent providers throughout product discovery, scoping, development, rollout, and maintenance.
  • Identify real-world challenges from practices and translate them into product requirements and process improvements.
  • Develop and deliver educational resources, such as guides, presentations, and webinars, to help practices use point-of-care genomic testing recommendations, orders, and results in personalized patient care.
  • Explain genomic concepts to Flatiron colleagues and describe their impact on product design and user experience.
  • Partner with internal stakeholders to align clinical workflows, product features, and business objectives.
  • Participate in multidisciplinary discussions about the clinical implications of genomics in oncology care.
  • Stay current on molecular diagnostics, targeted therapies, and precision medicine guidelines to inform product innovation.

Benefits

  • Flexible work hours and flexible paid time off.
  • Comprehensive compensation package.
  • 401(k) contribution.
  • Financial health resources, including one-on-one financial advice.
  • Mental well-being tools and services.
  • Parental benefits and policies, including family-building care and generous leave.
  • Path-to-parenthood programs supporting fertility, adoption, and surrogacy.
  • Travel support for safe healthcare services.
  • Continuous learning support and inclusion and belonging initiatives.
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