Chief of Staff to the CEO

OpenLoop Health•Des Moines, IA

About The Position

OpenLoop Health is seeking a strategic, entrepreneurial, and execution-oriented Chief of Staff to serve as a trusted partner to the CEO and lead important strategic initiatives. The role combines driving strategic alignment and operational effectiveness within the Office of the CEO with independently building and operationalizing new businesses, subsidiaries, and strategic initiatives from zero to one. The Chief of Staff partners with the CEO on enterprise decisions across strategy, finance, operations, and organization; translates the CEO’s priorities into an enterprise plan; and drives measurable outcomes. The role owns Board meeting preparation and follow-up, the executive operating cadence, and the operating mechanisms needed to improve ownership, decision-making, and cross-functional execution. The position also sets the vision and execution roadmap for new businesses, leads them from concept to launch, establishes new and acquired entities in coordination with relevant functions, and owns post-acquisition integration and cross-company alignment. It defines success metrics and governance for new businesses and transitions them to permanent leaders once operational.

Requirements

7 to 12+ years of experience across finance, investing, corporate development, and business operations.
A first chapter in investment banking, private equity, venture capital, or M&A advisory.
Strong financial modeling, analytical, and transaction-evaluation skills.
Hands-on operating experience at an early-stage or high-growth startup, ideally launching, scaling, or transforming a business or function as a co-founder, GM, head of operations, or similar.
Track record of leading complex, ambiguous initiatives from concept to execution.
Experience working directly with senior executives and influencing cross-functional leaders without formal authority.
Exceptional written and verbal communication, including Board-level presentations.
Accountability for strategic, financial, and operational outcomes, not only recommendations.
Ability to work self-directed, turning the CEO’s direction into action with minimal oversight.
Comfort with ambiguous, high-stakes problems where neither the answer nor the infrastructure exists yet.
Trusted-advisor capability with founders and executives, with builder experience at high-growth companies.
Investor-trained operator who has valued businesses and then built them.
Board-ready communication that frames decisions, trade-offs, and recommendations for the CEO, Board, and investors.
Discretion with sensitive matters across deals, governance, and people.

Nice To Haves

Early-stage or high-growth startup operating experience, ideally launching, scaling, or transforming a business or function.
Experience as a co-founder, GM, head of operations, or in a similar role.

Responsibilities

Act as the CEO’s strategic partner on enterprise decisions across strategy, finance, operations, and organization.
Translate the CEO’s top priorities into an enterprise plan with clear owners and drive them to measurable outcomes.
Own Board meeting planning, materials, and follow-up with the CEO, CFO, COO, and General Counsel.
Own the executive operating cadence and hold leaders accountable for key decisions and commitments.
Design operating mechanisms that address gaps in ownership, decision-making, and cross-functional execution.
Set the vision and execution roadmap for new businesses and lead them from concept to launch with accountability for results.
Lead the operational establishment of new and acquired entities, aligning Legal, Finance, HR, IT, Compliance, and Operations.
Own post-acquisition integration and cross-company alignment after close, partnering with Corporate Development on diligence and planning.
Define success metrics and governance for each new business, and transition it to a permanent leader once it runs.